Introduction The epidemiology of primary immunodeficiencies (PID) is not well documented
in Africa. The objective of this study was to describe the spectrum of PID at a tertiary …

Inborn errors of immunity (IEI), formerly known as primary immunodeficiency disorders
(PIDs), are inherited disorders caused by damaging germline variants in single genes …

Primary immunodeficiencies (PIDs) are genetic disorders impairing host immunity, leading
to life-threatening infections, autoimmunity, and/or malignancies. Genomic technologies …

Abstract Purpose Primary immunodeficiency diseases (PIDs) are inherited disorders of the
immune system resulting in increased susceptibility to unusual infections and predisposition …

The field of Primary Immunodeficiencies (PID) is growing fast. Over 400 diseases are
defined and characterized by recurrent or chronic infections, autoimmunity, allergy …

Background: Primary Immunodeficiencies (PIDs) are a heterogeneous group of genetic
immune disorders. While some PIDs can manifest with more than one phenotype, signs, and …

Throughout the world, primary immunodeficiencies (PI) are largely undiagnosed and
underreported. Many patients do not receive an accurate and timely diagnosis, which is …

The number of genetically defined Primary Immunodeficiency Diseases (PID) has increased
exponentially, especially in the past decade. The biennial classification published by the …

Background Molecular genetics techniques are an essential diagnostic tool for primary
immunodeficiency diseases (PIDs). The use of next-generation sequencing (NGS) provides …

Background Primary immunodeficiency (PID) disorders are a heterogeneous group of
inherited disorders caused by a variety of monogenetic immune defects. Thus far, mutations …