HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms
Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the
human genome with some regions of high LD interspersed with regions of low LD. Such LD …
human genome with some regions of high LD interspersed with regions of low LD. Such LD …
Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies
Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the
human genome with some regions of high LD interspersed by regions of low LD. A small …
human genome with some regions of high LD interspersed by regions of low LD. A small …
Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome
TG Schulze, K Zhang, YS Chen, N Akula… - Human Molecular …, 2004 - academic.oup.com
Recent studies suggest that the genome is organized into blocks of haplotypes, and efforts
to create a genome-wide haplotype map of single-nucleotide polymorphisms (SNPs) are …
to create a genome-wide haplotype map of single-nucleotide polymorphisms (SNPs) are …
A dynamic programming algorithm for haplotype block partitioning
We develop a dynamic programming algorithm for haplotype block partitioning to minimize
the number of representative single nucleotide polymorphisms (SNPs) required to account …
the number of representative single nucleotide polymorphisms (SNPs) required to account …
Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs
F Takeuchi, K Yanai, T Morii, Y Ishinaga… - Genetics, 2005 - academic.oup.com
Single nucleotide polymorphisms (SNPs) have been proposed to be grouped into haplotype
blocks harboring a limited number of haplotypes. Within each block, the portion of …
blocks harboring a limited number of haplotypes. Within each block, the portion of …
HaploBlockFinder: haplotype block analyses
Recent studies have unveiled discrete block-like structures of linkage disequilibrium (LD) in
the human genome. We have developed a set of computer programs to analyze the block …
the human genome. We have developed a set of computer programs to analyze the block …
[HTML][HTML] Selection of genetic markers for association analyses, using linkage disequilibrium and haplotypes
Z Meng, DV Zaykin, CF Xu, M Wagner… - The American Journal of …, 2003 - cell.com
The genotyping of closely spaced single-nucleotide polymorphism (SNP) markers frequently
yields highly correlated data, owing to extensive linkage disequilibrium (LD) between …
yields highly correlated data, owing to extensive linkage disequilibrium (LD) between …
[HTML][HTML] The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates
M Nothnagel, K Rohde - The American Journal of Human Genetics, 2005 - cell.com
The definition of haplotype blocks of single-nucleotide polymorphisms (SNPs) has been
proposed so that the haplotypes can be used as markers in association studies and to …
proposed so that the haplotypes can be used as markers in association studies and to …
Haplotype block structures show significant variation among populations
N Liu, SL Sawyer, N Mukherjee… - … Official Publication of …, 2004 - Wiley Online Library
Recent studies suggest that haplotypes tend to have block‐like structures throughout the
human genome. Several methods were proposed for haplotype block partitioning and for …
human genome. Several methods were proposed for haplotype block partitioning and for …
Haplotype block definition and its application
We present a simple two-stage procedure to define haplotype blocks and construct a statistic
to test whether a polymorphism belongs to a block. Applying this method to the data of …
to test whether a polymorphism belongs to a block. Applying this method to the data of …