Subchondral bone plays a key role in the development of osteoarthritis, however,
epigenetics of subchondral bone has not been extensively studied. In this study, we …

Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …

Objective The aim of this study was to characterize the genome‐wide DNA methylation
profile of chondrocytes from knee and hip cartilage obtained from patients with osteoarthritis …

Background Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …

Objective The aim of this work was to characterize the genome-wide DNA methylation profile
of cartilage from three regions of tibial plateau isolated from patients with primary knee …

Objective To analyze the methylome of normal and osteoarthritic (OA) knee articular
cartilage and to determine the role of DNA methylation in the regulation of gene expression …

Epigenetic changes in articular chondrocytes are associated with osteoarthritis (OA) disease
progression. Numerous studies have identified differentially methylated cytosines in OA …

Objectives Transcriptional changes in cartilage can impact function by causing degradation
such as that which occurs during the development of osteoarthritis (OA). Epigenetic …

Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …

Objective Cartilage epigenetic changes are strongly associated with human osteoarthritis
(OA). However, the influence of individual environmental OA risk factors on these epigenetic …