Abstract A library of forty 7, 8-benzoflavone derivatives was synthesized and evaluated for
their inhibitory potential against cholesterol esterase (CEase). Among all the synthesized …

A series of phosphorylated flavonoids were synthesized and investigated in vitro as
inhibitors of pancreatic cholesterol esterase (CEase) and acetylcholinesterase (AChE). The …

Five flavones possessing one to four phenolic groups were fully phosphorylated efficiently
and the obtained compounds showed excellent pancreatic cholesterol esterase (CEase) …

Objective: To investigate the cholesterol esterase inhibitory activity of flavonoids using in
silico and in vitro studies. Methods: In this perspective, flavonoids like catechin, chalcone, 4 …

Primary hypercholesterolemia is the root cause for major health issues like coronary heart
disease and atherosclerosis. Regulating plasma cholesterol level, which is the product of …

Tri‐N‐alkylcarbamylphloroglucinols (1–4) are synthesized as conformationally constrained
analogs of triacylglycerols (TGs) to probe Jenck's proximity effect in the cholesterol esterase …

New drug discovery is considered broadly in terms of two kinds of investigational activities
such as exploration and exploitation. This study deals with the evaluation of the cholesterol …

We present a new class of inhibitors of pancreatic cholesterol esterase (CEase) based on
'priviledged'5-benzylidenerhodanine and 5-benzylidene-2, 4-thiazolidinedione structural …

Background: Esterase is an enzyme that splits esters into an acid and alcohol. Varieties of
esterases are present in human body to control diverse set of cellular processes and …

Cholesterol, one of the most essential components of cell adopted for executing various
physiological functions such as maintenance of cell membrane fluidity, synthesis of sex …