Analysis of the molecular mechanisms by flavonoids with potential use for osteoporosis prevention or therapy

V Rodríguez, M Rivoira, G Picotto… - Current Medicinal …, 2022 - ingentaconnect.com
Background: Osteoporosis is the most common skeletal disorder worldwide. Flavonoids
have the potential to alleviate bone alterations in osteoporotic patients with the advantage of …

The effects of flavonoids on bone

AA Welch, AC Hardcastle - Current osteoporosis reports, 2014 - Springer
Osteoporosis and fragility fractures are a growing problem for our aging population with
around 1 in 2 women and 1 in 5 men suffering from an osteoporotic fracture during their …

Re-appraising the role of flavonols, flavones and flavonones on osteoblasts and osteoclasts-A review on its molecular mode of action

S Sekaran, A Roy, L Thangavelu - Chemico-Biological Interactions, 2022 - Elsevier
Bone disorders have become a global concern illustrated with decreased bone mineral
density and disruption in microarchitecture of natural bone tissue organization. Natural …

[HTML][HTML] Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Osteoprotective effects of flavonoids: Evidence from in vivo and in vitro studies

L Cao, J Wang, Y Zhang, F Tian… - Molecular Medicine …, 2022 - spandidos-publications.com
Osteoporosis is a systemic bone disease characterized by decreased bone mass and
quality and bone micro‑architecture degradation. Its primary cause is disorder of bone …

Non-flavonoid polyphenols in osteoporosis: Preclinical evidence

D Bellavia, F Caradonna, E Dimarco, V Costa… - Trends in Endocrinology …, 2021 - cell.com
The development of progressive osteopenia and osteoporosis (OP) is due to the imbalance
between bone resorption and bone formation, determining a lower bone resistance, major …

Flavonoids in bone erosive diseases: perspectives in osteoporosis treatment

D Bellavia, E Dimarco, V Costa, V Carina… - Trends in Endocrinology …, 2021 - cell.com
Imbalance of bone homeostasis, with excessive bone resorption compared with bone
formation, leads to the development of progressive osteopenia leading to lower bone …

Phenolic phytochemicals and bone

V Habauzit, MN Horcajada - Phytochemistry Reviews, 2008 - Springer
Concerning the prevention of osteoporosis, recognized as a major public health problem,
nutrition may appear as an alternative strategy for optimizing health skeleton. The …

Flavonoid intake and bone health

CM Weaver, DL Alekel, WE Ward… - Journal of nutrition in …, 2012 - Taylor & Francis
Flavonoids, found in a wide diversity of plant foods from fruits and vegetables, herbs and
spices, essential oils, and beverages, have the most potential of dietary components for …

Role of phytochemicals in the prevention of menopausal bone loss: evidence from in vitro and in vivo, human interventional and pharmacokinetic studies

K Sharan, JA Siddiqui, G Swarnkar… - Current medicinal …, 2009 - ingentaconnect.com
Substantial body of data generated from cultured bone cells and rat models of osteoporosis
supports a significant bone-conserving effect of phytochemicals. Flavonoids including …