Effects of 6‐Hydroxyflavone on Osteoblast Differentiation in MC3T3‐E1 Cells

CH Lai, YW Wu, SD Yeh, YH Lin… - … and Alternative Medicine, 2014 - Wiley Online Library
Osteoblast differentiation plays an essential role in bone integrity. Isoflavones and some
flavonoids are reported to have osteogenic activity and potentially possess the ability to treat …

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

LG Ming, KM Chen, CJ Xian - Journal of cellular physiology, 2013 - Wiley Online Library
Increasingly natural products particularly flavonoids are being explored for their therapeutic
potentials in reducing bone loss and maintaining bone health. This study has reviewed …

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health

AC Ortiz, SOM Fideles, CHB Reis, MZ Bellini… - Biomolecules, 2022 - mdpi.com
Flavonoids are natural phytochemicals that have therapeutic effects and act in the
prevention of several pathologies. These phytochemicals can be found in seeds, grains, tea …

Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - Nutrients, 2023 - mdpi.com
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …

Association between dietary intake of flavonoid and bone mineral density in middle aged and elderly Chinese women and men

ZQ Zhang, LP He, YH Liu, J Liu, YX Su… - Osteoporosis …, 2014 - Springer
This large cross-sectional study examined the associations of dietary intakes of total
flavonoids and their subtypes with bone density in women and men. We found that greater …

Dietary nutraceuticals as backbone for bone health

MK Pandey, SC Gupta, D Karelia, PJ Gilhooley… - Biotechnology …, 2018 - Elsevier
Bone loss or osteoporosis, is a slow-progressing disease that results from dysregulation of
pro-inflammatory cytokines. The FDA has approved number of drugs for bone loss …

Naturally plant-derived compounds: role in bone anabolism

MN Horcajada, E Offord - Current molecular pharmacology, 2012 - ingentaconnect.com
From a nutritional point of view, several factors are involved in ensuring optimal bone health.
The most documented of these are calcium and vitamin D. However, it is now well …

[PDF][PDF] The osteogenic effect of bioactive flavonoid p-hydroxycinnamic acid: development in osteoporosis treatment

M Yamaguchi - OA Biotechnol, 2013 - Citeseer
Bone homeostasis is maintained through a balance between osteoblastic bone formation
and osteoclastic bone resorption. Ageing induces bone loss due to decreased osteoblastic …

Quercetin as an agent for protecting the bone: a review of the current evidence

SK Wong, KY Chin, S Ima-Nirwana - International journal of molecular …, 2020 - mdpi.com
Quercetin is a flavonoid abundantly found in fruits and vegetables. It possesses a wide
spectrum of biological activities, thus suggesting a role in disease prevention and health …

Beneficial effects of plant sources on the treatment of osteoporosis

I Süntar, E Küpeli Akkol - Current Drug Targets, 2013 - ingentaconnect.com
Osteoporosis causes bone loss, and makes bone to susceptible to fracture. The main cause
of osteoporosis is estrogen deficiency. Estrogen, calcitonin, calcium, vitamin D and …