The extracellular calcium-sensing receptor (CaSR) is a unique G protein–coupled receptor
(GPCR) activated by extracellular Ca 2+ and by other physiological cations including Mg 2+ …

It is now known that variations in extracellular calcium concentration exert diverse
physiologic effects in a variety of tissues that are mediated by a calcium-sensing receptor …

Calcium-sensing receptor (CaSR) is a G-protein coupled receptor identified as a essential
molecule for the regulation of parathyroid hormone (PTH) secretion by extracellular calcium …

The extracellular calcium-sensing receptor (CaR) is a versatile sensor of small, polycationic
molecules ranging from Ca2+ and Mg2+ through polyarginine, spermine, and neomycin …

The calcium-sensing receptor (CaR), a seven-transmembrane domain receptor belonging to
the G protein-coupled receptor family, is responsible for calcium-mediated signalling …

Aim Reduced calcium sensing receptor (CaSR) expression has been implicated in
parathyroid tumorigenesis, but the underlying mechanism remains elusive. Accordingly, we …

To investigate whether the effect of the calcimimetic AMG 641 and calcitriol on CaSR and
VDR expression could be separated from their ability to reduce parathyroid cell proliferation …

Abstract Purpose Calcium sensing receptor (CaSR), on the surface of normal parathyroid
cells, is essential for maintaining serum calcium levels. The normal pattern of CaSR …

Clinical studies have been performed to determine the effect of cinacalcet HCl (cinacalcet),
an allosteric modulator of the calcium-sensing receptor (CaR), on primary …

Calcium participates in most of the biological processes in the human body. The calcium
sensing receptor (CaSR), as an important regulator of calcium homeostasis, is expressed in …