A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease

DK Lahiri, MR Farlow, K Sambamurti… - Current drug …, 2003 - ingentaconnect.com
Alzheimer's disease (AD), a progressive, degenerative disorder of the brain, is believed to
be the most common cause of dementia amongst the elderly. AD is characterized by the …

Neurodegenerative pathways in Alzheimer's disease: a review

AK Ramachandran, S Das, A Joseph… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

MW Marlatt, KM Webber, PI Moreira… - Current medicinal …, 2005 - ingentaconnect.com
In recent years, Alzheimer disease (AD) has received great attention as an incurable and
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …

Current drug targets for Alzheimer's disease treatment

DK Lahiri, MR Farlow, NH Greig… - Drug development …, 2002 - Wiley Online Library
Abstract Alzheimer's disease (AD), the most common form of dementia among the elderly, is
a progressive, degenerative disorder of the brain with a loss of memory and cognition. A …

[HTML][HTML] Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease

K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent, progressive and multifaceted
neurodegenerative disorder associated with cognition, memory and behavioural …

[HTML][HTML] Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease

T Guo, D Zhang, Y Zeng, TY Huang, H Xu… - Molecular …, 2020 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …

Alzheimer's disease: a general introduction and pathomechanism

VH Finder - Journal of Alzheimer's disease, 2010 - content.iospress.com
Alzheimer's disease (AD) is the most common form of dementia, which affects more than 35
million people worldwide with increasing tendency. Satisfying therapies and prevention are …

[HTML][HTML] Current therapeutic targets for Alzheimer's disease

A Chaudhary, PK Maurya, BS Yadav, S Singh… - Journal of …, 2018 - jbiomed.com
Alzheimer's disease (AD) is one of the most common multifactorial diseases, including a
range of abnormal cellular/molecular processes occurring in different regions of the brain …

Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application

C Pietrzik, C Behl - International journal of experimental …, 2005 - Wiley Online Library
To date, various strategies have been developed in order to prevent or to slow down the
progression of Alzheimer's disease (AD). Despite the medical need for an effective …