[HTML][HTML] Depressive disorder and antidepressants from an epigenetic point of view
Depressive disorder is a complex, heterogeneous disease that affects approximately 280
million people worldwide. Environmental, genetic, and neurobiological factors contribute to …
million people worldwide. Environmental, genetic, and neurobiological factors contribute to …
Epigenetic alterations in depression and antidepressant treatment
Epigenetic modifications control chromatin structure and function, and thus mediate changes
in gene expression, ultimately influencing protein levels. Recent research indicates that …
in gene expression, ultimately influencing protein levels. Recent research indicates that …
Epigenetics and depression: return of the repressed
VS Dalton, E Kolshus, DM McLoughlin - Journal of affective disorders, 2014 - Elsevier
Introduction Epigenetics has recently emerged as a potential mechanism by which adverse
environmental stimuli can result in persistent changes in gene expression. Epigenetic …
environmental stimuli can result in persistent changes in gene expression. Epigenetic …
Value of genetic and epigenetic testing as biomarkers of response to antidepressant treatment
H Frieling, A Tadić - International Review of Psychiatry, 2013 - Taylor & Francis
Major depressive disorder (MDD) is one of the most prevalent and disabling psychiatric
disorders worldwide and therefore an important public health priority. The selection process …
disorders worldwide and therefore an important public health priority. The selection process …
[HTML][HTML] DNA methylation in depression and depressive-like phenotype: biomarker or target of pharmacological intervention?
Major depressive disorder (MDD) is a debilitating psychiatric disorder, the third leading
global cause of disability. Regarding aetiopathogenetic mechanisms involved in the onset of …
global cause of disability. Regarding aetiopathogenetic mechanisms involved in the onset of …
[HTML][HTML] The molecular basis of depression: implications of sex-related differences in epigenetic regulation
A Kawatake-Kuno, T Murai, S Uchida - Frontiers in Molecular …, 2021 - frontiersin.org
Major depressive disorder (MDD) is a leading cause of disability worldwide. Although the
etiology and pathophysiology of MDD remain poorly understood, aberrant neuroplasticity …
etiology and pathophysiology of MDD remain poorly understood, aberrant neuroplasticity …
Epigenetics of depression
Major depressive disorder (MDD) is a leading cause of disability worldwide and is
associated with poor psychological, medical, and socioeconomic outcomes. Although much …
associated with poor psychological, medical, and socioeconomic outcomes. Although much …
Epigenetics, depression and antidepressant treatment
The heritability of major depression has been documented in a number of epidemiologic
studies. Twin studies have estimated the heritability at about 37% and these estimation can …
studies. Twin studies have estimated the heritability at about 37% and these estimation can …
Molecular studies of major depressive disorder: the epigenetic perspective
J Mill, A Petronis - Molecular psychiatry, 2007 - nature.com
Major depressive disorder (MDD) is a common and highly heterogeneous psychiatric
disorder encompassing a spectrum of symptoms involving deficits to a range of cognitive …
disorder encompassing a spectrum of symptoms involving deficits to a range of cognitive …
Moving pharmacoepigenetics tools for depression toward clinical use
Background Major depressive disorder (MDD) is a leading cause of disability worldwide,
and over half of patients do not achieve symptom remission following an initial …
and over half of patients do not achieve symptom remission following an initial …