Epigenetic change as the major mediator of fetal programming in humans: are we there yet?
R Saffery - Annals of Nutrition and Metabolism, 2014 - karger.com
The developmental origins of health and disease (DOHaD) hypothesis predicts that
environmental exposures experienced early in life have the potential to modify the risk …
environmental exposures experienced early in life have the potential to modify the risk …
Epigenetic epidemiology of the developmental origins hypothesis
RA Waterland, KB Michels - Annu. Rev. Nutr., 2007 - annualreviews.org
Extensive human epidemiologic and animal model data indicate that during critical periods
of prenatal and postnatal mammalian development, nutrition and other environmental stimuli …
of prenatal and postnatal mammalian development, nutrition and other environmental stimuli …
Epigenetic studies in developmental origins of health and disease: pitfalls and key considerations for study design and interpretation
L Yamada, S Chong - Journal of developmental origins of health and …, 2017 - cambridge.org
The field of Developmental Origins of Health and Disease (DOHaD) seeks to understand the
relationships between early-life environmental exposures and long-term health and disease …
relationships between early-life environmental exposures and long-term health and disease …
Developmental origins of health and disease: environmental exposures
The developmental origins of health and disease (DOHaD) approach has evolved over the
past 20 years, and the current hypothesis proposes that fetal adaptations to intrauterine and …
past 20 years, and the current hypothesis proposes that fetal adaptations to intrauterine and …
Epigenetic responses and the developmental origins of health and disease
D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …
successful postnatal life. Based on the stressors during gestation, the pregnant female …
Epigenetics and DOHaD: from basics to birth and beyond
T Bianco-Miotto, JM Craig, YP Gasser… - … origins of health and …, 2017 - cambridge.org
Developmental origins of health and disease (DOHaD) is the study of how the early life
environment can impact the risk of chronic diseases from childhood to adulthood and the …
environment can impact the risk of chronic diseases from childhood to adulthood and the …
DOHaD and the periconceptional period, a critical window in time
Environmental conditions can modulate the developmental program and have enduring
consequences on the life cycle, affecting long-term health and disease risk through to …
consequences on the life cycle, affecting long-term health and disease risk through to …
Epigenetics–potential contribution to fetal programming
JC Mathers, JA McKay - … Nutrition Programming and Health Outcomes in …, 2009 - Springer
Whilst the primary DNA sequence sets the limits of potential gene expression, the pattern of
gene expression in a given cell under particular circumstances is determined by several …
gene expression in a given cell under particular circumstances is determined by several …
Epigenetics as the mediator of fetal programming of adult onset disease: what is the evidence?
R Saffery, B Novakovic - Acta obstetricia et gynecologica …, 2014 - Wiley Online Library
Abstract The Developmental Origins of Health and Disease hypothesis describes how early
life environmental factors influence development in a way that impacts later health and …
life environmental factors influence development in a way that impacts later health and …
Life-long implications of developmental exposure to environmental stressors: new perspectives
P Grandjean, R Barouki, DC Bellinger… - …, 2015 - academic.oup.com
Abstract The Developmental Origins of Health and Disease (DOHaD) paradigm is one of the
most rapidly expanding areas of biomedical research. Environmental stressors that can …
most rapidly expanding areas of biomedical research. Environmental stressors that can …