Reactive oxygen and nitrogen species are currently considered not only harmful byproducts
of aerobic respiration but also critical mediators of redox signaling. The molecules and the …

Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

Cellular redox homeostasis is an essential and dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and regulates a plethora of biological …

This first entry-level guide to the multifaceted field takes readers one step further than
existing textbooks. In an easily accessible manner, the authors integrate the biochemistry …

Redox biology has evolved from studies of the pathology that involves oxidants to an
understanding of how oxidants participate in normal as well as aberrant signal transduction …

Significance: The redox code is a set of principles that defines the positioning of the
nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox systems …

Generation of reactive oxygen species (ROS) by plasma membrane–localized NADPH
oxidase (Nox 2) is a major mechanism of cell signaling associated with activation of the …

Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …

Reactive oxygen species (ROS) 2 and reactive nitrogen species (RNS) have long been
implicated in damaging biomolecular components including lipids, proteins, and DNA (1) …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …