Synthesis and evaluation of isonicotinoyl hydrazone derivatives as antimycobacterial and anticancer agents

HS Naveen Kumar, T Parumasivam, F Jumaat… - Medicinal Chemistry …, 2014 - Springer
A new series of isonicotinoyl hydrazone derivatives (3a–3o) have been synthesized,
characterized and evaluated for in vitro antimycobacterial activity against M. tuberculosis …

Synthesis and antimycobacterial activity of a novel series of isonicotinylhydrazide derivatives

S Jaju, M Palkar, V Maddi, P Ronad… - … der Pharmazie: An …, 2009 - Wiley Online Library
A novel series of 14 new isonicotinyl hydrazide derivatives 2a–g, 3a–g containing a 4‐
thiazolidinone/2‐azetidinone nucleus were synthesized by reacting N′‐substituted …

Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones

D Sriram, P Yogeeswari, K Madhu - Bioorganic & medicinal chemistry …, 2005 - Elsevier
The purpose of this study was to prepare various isoniazid derivatives by introducing the
isoniazid pharmacophore into several molecules and screening for antimycobacterial …

Synthesis and antitubercular activity of heteroaromatic isonicotinoyl and 7-chloro-4-quinolinyl hydrazone derivatives

ML Ferreira, RSB Gonçalves, LNF Cardoso… - The Scientific World …, 2010 - hindawi.com
Two series of N'(E)-heteroaromatic-isonicotinohydrazide derivatives (3a-f and 4a-b) and 1-(7-
chloroquinolin-4-yl)-2-[(heteroaromatic) methylene] hydrazone derivatives (5a-f and 6a-b) …

Synthesis and anti-mycobacterial activity of (E)-N′-(monosubstituted-benzylidene) isonicotinohydrazide derivatives

MC da Silva Lourenco, M de Lima Ferreira… - European Journal of …, 2008 - Elsevier
A series of 22 (E)-N′-(monosubstituted-benzylidene) isonicotinohydrazide derivatives have
been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium …

[HTML][HTML] Design, synthesis and antitubercular activity of certain nicotinic acid hydrazides

WM Eldehna, M Fares, MM Abdel-Aziz, HA Abdel-Aziz - Molecules, 2015 - mdpi.com
Three series of 6-aryl-2-methylnicotinohydrazides 4a–i, N′-arylidene-6-(4-bromophenyl)-2-
methylnicotino hydrazides 7a–f, and N′-(un/substituted 2-oxoindolin-3-ylidene)-6-(4 …

[HTML][HTML] 4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents

M Krause, H Foks, D Ziembicka… - European journal of …, 2020 - Elsevier
The series of new 4-substituted picolinohydrazonamides were synthesized (6-25) and
evaluated for tuberculostatic activity. Compounds having a hydrophilic cyclic amine such as …

Design and synthesis of some new quinoline-3-carbohydrazone derivatives as potential antimycobacterial agents

S Eswaran, AV Adhikari, NK Pal… - Bioorganic & Medicinal …, 2010 - Elsevier
A series of 26 new quinoline derivatives carrying active pharmacophores has been
synthesized and evaluated for their in vitro antituberculosis activity against Mycobacterium …

New indole and indazole derivatives as potential antimycobacterial agents

VT Angelova, T Pencheva, N Vassilev… - Medicinal Chemistry …, 2019 - Springer
The study reports on the synthesis and in vitro assessment of the antimycobacterial activity
of a series of new indole-and indazole-based aroylhydrazones evaluated against …

Synthesis and antimycobacterial activity of some isonicotinoylhydrazones

MT Cocco, C Congiu, V Onnis, MC Pusceddu… - European journal of …, 1999 - Elsevier
Aseries of isonicotinoylhydrazones 2 were prepared by addition of some aryloxyacetonitriles
with isonicotinoylhydrazine in basic medium. These compounds have been further reacted …