miRNAs: potential as biomarkers and therapeutic targets for cancer

A Chakrabortty, DJ Patton, BF Smith, P Agarwal - Genes, 2023 - mdpi.com
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …

The role of MicroRNAs in human cancer

Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

Exploring miRNA based approaches in cancer diagnostics and therapeutics

S Mishra, T Yadav, V Rani - Critical reviews in oncology/hematology, 2016 - Elsevier
MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …

MicroRNAs as potential biomarkers in cancer: opportunities and challenges

H Lan, H Lu, X Wang, H Jin - BioMed research international, 2015 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

MicroRNAs: novel regulators in the hallmarks of human cancer

K Ruan, X Fang, G Ouyang - Cancer letters, 2009 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs of 18–25 nucleotides in length that
function as negative regulators. miRNAs post-transcriptionally regulate gene expression by …

MicroRNAs: a puzzling tool in cancer diagnostics and therapy

B D'ANGELO, E Benedetti, A Cimini… - Anticancer …, 2016 - ar.iiarjournals.org
MicroRNAs (miRNAs) constitute a dominating class of small RNAs that regulate diverse
cellular functions. Due the pivotal role of miRNAs in biological processes, a deregulated …

MicroRNA (miRNA) in cancer

KB Reddy - Cancer cell international, 2015 - Springer
In recent years, there has been a tremendous and growing interest among researchers to
investigate the role of mircoRNA (miRNA) in normal cellular as well as in disease processes …

MicroRNAs as therapeutic targets in cancer

SP Nana-Sinkam, CM Croce - Translational Research, 2011 - Elsevier
Cancer remains a worldwide epidemic. An improved understanding of the underlying
molecular mechanisms and development of effective targeted therapies are still required for …

MicroRNAs and cancer; an overview

L Tutar, E Tutar, Y Tutar - Current pharmaceutical …, 2014 - ingentaconnect.com
MiRNAs are a family of small, endogenous, and evolutionarily conserved non-coding
ribonucleic acids that have been involved in the regulation of several essential, cellular, and …

MicroRNA expression and function in cancer

R Garzon, M Fabbri, A Cimmino, GA Calin… - Trends in molecular …, 2006 - cell.com
MicroRNAs are small non-coding RNAs of 19–24 nucleotides in length that downregulate
gene expression during various crucial cell processes such as apoptosis, differentiation and …