SOD, oxidative stress and human pathologies: a brief history and a future vision

JM McCord, MA Edeas - Biomedicine & Pharmacotherapy, 2005 - Elsevier
Superoxide dismutase (SOD) has now been known for 35 years. While the superoxide
radical and SOD have been implicated in many disease states including inflammatory …

[PDF][PDF] Superoxide dismutases: a physiopharmacological update

A Valdivia, S Perez-Alvarez… - Journal of physiology …, 2009 - researchgate.net
(minireview). J Physiol Biochem, 65 (2), 195-208, 2009. Reactive oxygen species (ROS) are
known participants in several cellular processes. Superoxide anion radical, one example of …

The basic and applied aspects of superoxide dismutase

A Bafana, S Dutt, A Kumar, S Kumar… - Journal of Molecular …, 2011 - Elsevier
Superoxide dismutase (SOD) is among the most potent antioxidants known in nature and is
an important constituent of cellular defence against oxidative stress. The enzyme shows …

Superoxide dismutases (SODs) and SOD mimetics

GEO Borgstahl, RE Oberley-Deegan - Antioxidants, 2018 - mdpi.com
Superoxide dismutase (SOD) is the only known enzyme to directly scavenge a free radical.
Specifically, SOD dismutes superoxide to oxygen and hydrogen peroxide with high …

Book review: role of superoxide dismutases in oxidative damage and neurodegenerative disorders

CM Maier, PH Chan - The Neuroscientist, 2002 - journals.sagepub.com
In recent years, oxidative stress has been implicated in a variety of degenerative processes,
diseases, and syndromes. Some of these include atherosclerosis, myocardial infarction …

Extracellular superoxide dismutase in biology and medicine

CL Fattman, LM Schaefer, TD Oury - Free Radical Biology and Medicine, 2003 - Elsevier
Accumulated evidence has shown that reactive oxygen species (ROS) are important
mediators of cell signaling events such as inflammatory reactions (superoxide) and the …

On the origin of superoxide dismutase: an evolutionary perspective of superoxide-mediated redox signaling

AJ Case - Antioxidants, 2017 - mdpi.com
The field of free radical biology originated with the discovery of superoxide dismutase (SOD)
in 1969. Over the last 5 decades, a plethora of research has been performed in species …

Superoxide dismutases and their impact upon human health

F Johnson, C Giulivi - Molecular aspects of medicine, 2005 - Elsevier
Superoxide dismutases (SOD), a group of metal-containing enzymes, have a vital anti-
oxidant role in human health, conferred by their scavenging of one of the reactive oxygen …

Superoxide dismutase: an emerging target for cancer therapeutics

EA Hileman, G Achanta, P Huang - Expert Opinion on Therapeutic …, 2001 - Taylor & Francis
Superoxide dismutase (SOD) is a critical enzyme responsible for the elimination of
superoxide radicals and is considered to be a key anti-oxidant in aerobic cells. Cellular …

Expanding roles of superoxide dismutases in cell regulation and cancer

M Che, R Wang, X Li, HY Wang, XFS Zheng - Drug discovery today, 2016 - Elsevier
Highlights•Superoxide dismutases (SODs) have important regulatory functions in
metabolism, signalling and transcription.•SODs are crucial for cancer cell growth …