Fluconazole and amphotericin B were compared in the prophylaxis and treatment of
Candida albicans aortic endocarditis in a rabbit model. In the prophylaxis study, catheterized …

Amphotericin B (AmB) and fluconazole, administered intraperitoneally for 7 days, were
compared in a rabbit model for Candida albicans endocarditis. When given early, AmB was …

Amphotericin B (1 mg/kg of body weight, intravenous) and fluconazole (100 mg/kg,
intraperitoneal) were compared in the prophylaxis of experimental Candida endocarditis …

Amphotericin B and fluconazole were compared for the treatment of experimental Candida
endocarditis caused by Candida tropicalis and C. parapsilosis. Rabbits received no therapy …

The efficacy of fluconazole, a bis-triazole antifungal agent, for prophylaxis and treatment of
endocarditis due to Candida albicans and Candida parapsilosis is assessed in a rabbit …

Although there are an increasing number of new antifungal agents available, the morbidity
and mortality due to invasive mycoses remain high. The high rates of polyene toxicities and …

We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine
(5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit …

Endocarditis caused by Candida albicans was induced in rabbits after insertion of a catheter
across the aortic valve. The mean survival time of 34 rabbits was 26 days. Only 7% of …

Recent observations demonstrated that fluconazole plus cyclosporine (Cy) synergistically
killed Candida albicans in vitro. This combination was tested in rats with C. albicans …

In vitro time-kill studies and a rabbit model of endocarditis and pyelonephritis were used to
define the impact that the order of exposure of Candida albicans to fluconazole (FLC) and …