[HTML][HTML] A bioprosthetic heart valve prepared by copolymerization of 2-isocyanatoethyl methacrylate modified pericardium and functional monomer

C Zheng, K Ding, X Huang, L Yang, Y Lei… - Composites Part B …, 2022 - Elsevier
Bioprosthetic heart valves (BHVs), mostly fabricated from glutaraldehyde crosslinked
porcine or bovine pericardium, have been increasingly used in clinic with the application of …

[HTML][HTML] Nonglutaraldehyde crosslinked bioprosthetic heart valves based on 2-isocyanatoethyl methacrylate crosslinked porcine pericardium with improved properties …

C Zheng, K Ding, X Huang, M Li, B Wu, Y Lei… - Composites Part B …, 2022 - Elsevier
Valvular heart diseases (VHD) have a high incidence in the elderly, and the morbidity and
fatality rate of VHD increase gradually. To save the lives of patients at the end stage of VHD …

Poly (2-methoxyethyl acrylate) coated bioprosthetic heart valves by copolymerization with enhanced anticoagulant, anti-inflammatory, and anti-calcification properties

X Liang, Y Lei, K Ding, X Huang, C Zheng… - Journal of Materials …, 2022 - pubs.rsc.org
Commercial glutaraldehyde (Glut) cross-linked bioprosthetic heart valves (BHVs) fabricated
from the pericardium have become the most popular choice for treating heart valve …

[HTML][HTML] Double bond crosslinked and phosphocholinated biological heart valve with robust antithrombogenicity, durability and anticalcification property

C Zheng, X Huang, K Ding, D Kuang, L Yang… - Composites Part B …, 2023 - Elsevier
Glutaraldehyde crosslinked biological heart valves (BHVs) are increasingly implanted with
development of transcatheter heart valve implantation. While poor cytocompatibility and …

Arginine-grafted porcine pericardium by copolymerization to improve the cytocompatibility, hemocompatibility and anti-calcification properties of bioprosthetic heart …

X Liang, C Zheng, K Ding, X Huang, S Zhang… - Journal of Materials …, 2022 - pubs.rsc.org
Bioprosthetic heart valves (BHVs) have been used widely due to the development of
transcatheter heart valve replacement technology. However, glutaraldehyde crosslinked …

Cross-linking porcine pericardium by 3, 4-dihydroxybenzaldehyde: a novel method to improve the biocompatibility of bioprosthetic valve

B Wu, C Zheng, K Ding, X Huang, M Li… - …, 2020 - ACS Publications
Heart valve replacement is an effective therapy for patients with moderate to severe valvular
stenosis or regurgitation. Most bioprosthetic heart valves applied clinically are based on …

Dual-crosslinked bioprosthetic heart valves prepared by glutaraldehyde crosslinked pericardium and poly-2-hydroxyethyl methacrylate exhibited improved …

X Huang, C Zheng, K Ding, S Zhang, Y Lei, Q Wei… - Acta Biomaterialia, 2022 - Elsevier
Bioprosthetic heart valves (BHVs) have been widely used due to the revolutionary
transcatheter aortic valve replacement (TAVR) techniques but suffer from a limited lifespan …

A PEGylation method of fabricating bioprosthetic heart valves based on glutaraldehyde and 2-amino-4-pentenoic acid co-crosslinking with improved …

K Ding, C Zheng, X Huang, S Zhang, M Li, Y Lei… - Acta Biomaterialia, 2022 - Elsevier
With the development of diagnostic techniques, the incidence of bioprosthetic heart valve
thrombosis (BHVT) is found to be seriously underestimated. Developing bioprosthetic heart …

Cross-linking methacrylated porcine pericardium by radical polymerization confers enhanced extracellular matrix stability, reduced calcification, and mitigated immune …

L Jin, G Guo, W Jin, Y Lei, Y Wang - ACS biomaterials science & …, 2019 - ACS Publications
The aging population and the development of transcatheter aortic valve replacement (TAVR)
technology largely expand the usage of bioprosthetic heart valves (BHVs) in patients. Almost …

[HTML][HTML] A bioprosthetic heart valve material prepared by copolymerization of 2-Amino-4-pentanoic acid modified pericardium and N, N-Dimethylacrylamide

K Ding, C Zheng, X Huang, L Yang, Y Lei… - Composites Part B …, 2022 - Elsevier
Bioprosthetic heart valve thrombosis (BHVT) is no longer considered a rare clinical entity in
recent years and could cause valve motion abnormalities, which requires reoperation …