Dialysate composition is a critical aspect of the hemodialysis prescription. Despite this, trial
data are almost entirely lacking to help guide the optimal dialysate composition. Often, the …

An optimal dialysate bicarbonate concentration is one that prevents postdialysis alkalemia
and predialysis acidosis. The bicarbonate requirements in any patient will depend on the …

Background Most hemodialysis patients worldwide are treated with bicarbonate dialysis
using sodium bicarbonate as the base. Few studies have assessed outcomes of patients …

In two recent CKJ reviews, experts (Basile and Lomonte and Locatelli et al.) have reviewed
haemodialysate composition. A long-neglected issue, observational studies have …

Oligo‐anuric individuals receiving hemodialysis (HD) are dependent on the dialysis
machine to regulate sodium and water balance. Interest in adjusting the dialysate sodium …

Metabolic acidosis is a common complication of chronic kidney disease; it is typically caused
by the accumulation of sulfate, phosphorus, and organic anions. Metabolic acidosis is …

The optimal approach to managing acid-base balance is less well defined for patients
receiving hemodialysis than for those receiving peritoneal dialysis. Interventional studies in …

Dialysate prescription is evolving as new technology allows greater opportunity to alter
dialysate constituents throughout dialysis, providing scope for tailored prescription for an …

Abstract Background Although citrate dialysate (CiDi) is regarded to be safe, dialysis
modalities using higher dialysate volumes, like haemodiafiltration (HDF), may expose …

Background Citric acid-based bicarbonate dialysate (CiD) is increasingly used in
haemodialysis (HD) to improve haemodynamic tolerance and haemocompatibility …