Many studies have demonstrated that the endocannabinoid system (ECS) is altered in
different tumor types, including colon cancer. However, little is known about the role of the …

Changes in the regulation of endocannabinoid production, together with an altered
expression of their receptors are hallmarks of cancer, including colorectal cancer (CRC) …

The pharmacological activation of the cannabinoid receptor type 2, CB 2, has been shown to
elicit anti-tumoral mechanisms in different cancer types. However, little is known about its …

The cannabinoid system has been considered to be a potential target of colorectal
carcinoma therapy. The aim of this study was to address the correlation between …

Objective. Cannabinoids are a class of compounds that have the ability to activate two
specific receptor subtypes, the cannabinoid CB1 and CB2 receptors. CB1 receptor is a G …

Although endocannabinoid signaling is important for certain aspects of gastrointestinal
homeostasis, the role of the cannabinoid receptors (CB) in colorectal cancer has not been …

Increasing evidence suggest the role of the cannabinoid receptors (CBs) in the control of cell
survival or death and signaling pathways involved in tumor progression. Cancer cell lines …

Cannabinoid receptors, CB1 and CB2, have been implicated as emerging targets for cancer
therapy. Herein, we investigated the potential regulation mechanism of CB1 and its …

Colorectal cancer (CRC) is between the top three occurring cancers worldwide. The
anticancer effects of Cannabinoid receptor 2 (CB 2) agonist (GW833972A) in the presence …

CB1 and CB2 are multifunctional cannabinoid-specific receptors considered to be involved
in inhibition of tumor development. To elucidate their roles in hepatocarcinogenesis, we …