Preparation of NK-enriched LAK cells--their potential cytotoxic and ADCC activities
Y Kobayashi, T Sudo, N Matsushita… - Gan to Kagaku ryoho …, 2003 - europepmc.org
We examined several culture methods to induce proliferation of natural killer (NK) cells from
peripheral blood mononuclear cells (PBMC). In the presence of IL-2, a remarkable …
peripheral blood mononuclear cells (PBMC). In the presence of IL-2, a remarkable …
Differential oncolytic effect of NK-enriched subsets in long-term interleukin-2 cultures.
PR Fuchshuber, E Lotzova - Lymphokine and cytokine research, 1992 - europepmc.org
The aim of this study was to characterize the oncolytic efficacy of human natural killer (NK)
cell subsets generated from highly NK-enriched population in long-term IL-2 cultures. NK …
cell subsets generated from highly NK-enriched population in long-term IL-2 cultures. NK …
[PDF][PDF] NK cell-based immunotherapy for treating cancer: will it be promising
D Cho, S Kim, WE Carson - Korean J Hematol, 2011 - synapse.koreamed.org
The characterization of natural killer (NK) cells initially occurred in the 1970s and 1980s as a
result of efforts by investigators such as Rolf Kiessling and Ronald Heberman. It was …
result of efforts by investigators such as Rolf Kiessling and Ronald Heberman. It was …
Differential modulation of LAK and ADCC functions of natural killer cells from AK-5 tumor-bearing rats by IL-2, IL-12 and IFN-gamma.
K Muralikrishna, C Varalakshmi… - Cytokines, cellular & …, 1997 - europepmc.org
Modulation of NK cell activity by various lymphokines is well documented. Freshly isolated
NK cells exhibit natural cytotoxicity (NC) and antibody-dependent cellular cytotoxicity …
NK cells exhibit natural cytotoxicity (NC) and antibody-dependent cellular cytotoxicity …
[HTML][HTML] A Wilms tumor cell line, HFWT, can greatly stimulate proliferation of CD56+ human natural killer cells and their novel precursors in blood mononuclear cells
H Harada, S Watanabe, K Saijo, I Ishiwata… - Experimental …, 2004 - Elsevier
OBJECTIVE: A Wilms tumor cell line, HFWT, selectively stimulates expansion of natural killer
(NK) cells from human peripheral blood mononuclear cells (PBMC). In this study, we …
(NK) cells from human peripheral blood mononuclear cells (PBMC). In this study, we …
Clinical applications of natural Killer cells
Y Harada, K Teraishi, M Ishii, H Ban… - Natural Killer …, 2017 - books.google.com
Natural killer (NK) cells are an essential component of the innate immune system, and they
play a crucial role in immunity against malignancies. Recent advances in our understanding …
play a crucial role in immunity against malignancies. Recent advances in our understanding …
High release of tumor necrosis factor α, interferon γ and interleukin-6 by adherent lymphokine-activated killer cells phenotypically derived from T cells
J Koberda, L Bergmann, PS Mitrou… - Journal of cancer research …, 1991 - Springer
Adherent lymphokine-activated killer cells (A-LAK) are highly potent cytotoxic cells, which
are shown to be derived not only from natural killer (NK)/K cells but phenotypically also from …
are shown to be derived not only from natural killer (NK)/K cells but phenotypically also from …
Antitumor activity of NK cells
Q Yang, SR Goding, ME Hokland, PH Basse - Immunologic research, 2006 - Springer
NK cells have been shown to play an important role in the lungs with regards to tumor cell
clearance and resistance of this organ to metastases. Here, we have investigated whether …
clearance and resistance of this organ to metastases. Here, we have investigated whether …
Phenotypical analysis of effector cells on nonspecific cancer cell therapy
T Sudo, Y Kobayashi, N Matsushita… - Gan to Kagaku ryoho …, 2003 - europepmc.org
In the present study, we examined the contributions of lymphocyte subpopulations in
lymphokine activated killer (LAK) activity. LAK cells prepared from peripheral blood …
lymphokine activated killer (LAK) activity. LAK cells prepared from peripheral blood …
Natural killer (NK) cell and immunotherapy.
T Iino, S Takaishi - Nihon rinsho. Japanese Journal of Clinical …, 2017 - europepmc.org
Natural killer (NK) cells are innate lymphoid cells important for host defense against patho-
gens, and are also thought to play an important role in the immunosurveillance against can …
gens, and are also thought to play an important role in the immunosurveillance against can …