Background: Telomerase reverse transcriptase (TERT) promoter mutations have been
described in different pathological types of thyroid cancers (TC). After many types of …

The 2013 discovery of Telomerase reverse transcriptase (TERT) promoter mutations chr5,
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …

Objective Follicular-derived thyroid cancers generally have a good prognosis, but in a
minority of cases, they have an aggressive behavior and develop distant metastases, with …

Background: TERT encodes the reverse transcriptase component of telomerase, which adds
telomere repeats to chromosome ends, thus enabling cell replication. Telomerase activity is …

Context Little is known about the frequency of key mutations in thyroid cancer metastases
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …

Background: Distant metastases uncommonly occur in differentiated thyroid carcinoma
(DTC), but they are a frequent cause of thyroid cancer–related death. Genomic alterations in …

Background The association between telomerase reverse transcriptase (TERT) promoter
mutations and some clinical behaviors in thyroid cancer remains controversial and requires …

BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …

Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …

We performed a meta-analysis to elucidate the associations of the clinicopathological
characteristics and prognostic factors of papillary thyroid cancer (PTC) with TERT promoter …