Development of reliable vectors is a major challenge in gene therapy. Previous gene
transfer methods using non-viral vectors, such as liposomes or nanoparticles, have resulted …

Nanoparticles have an enormous potential for development in biomedical applications, such
as gene or drug delivery. We developed and characterized aminopropyltriethoxysilane …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …

Diverse polycationic polymers have been used as nonviral transfection agents. Here we
report the ability of colloidal silica particles with covalently attached cationic surface …

Abstract Development of efficient molecular medicines, including gene therapeutics, RNA
therapeutics, and DNA vaccines, depends on efficient means of transfer of DNA or RNA into …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

We have known for a while that silica is a promising candidate gene delivery vector. New in
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …

The nonviral gene delivery system is an attractive alternative to cancer therapy. A new kind
of gelatin-silica nanoparticles (GSNPs) was developed through a two-step sol–gel …

Porous silicon nanoparticles (pSiNPs) are a promising nanocarrier system for drug delivery
owing to their biocompatibility, biodegradability, and non-inflammatory nature. Here, we …