Abstract Purpose of Review The main purpose of this review, mainly based on preclinical
studies, is to summarize the pharmacological and biochemical evidence regarding natural …

Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …

Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

Colon cancer commonly develops from long-term chronic inflammation in the intestine and
seriously threatens human health. Natural polyphenols have been valued as a crucial …

Colorectal cancer is one of the leading causes of premature death in people worldwide. Due
to the fact that malignant conversion of normal colonic cells requires several steps and often …

Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …

Background A form of cancer that affects the rectum or colon (large intestine) is called
colorectal cancer (CRC). The main risk factors for CRC include dietary, lifestyle, and …

Simple Summary Colorectal cancer is a leading cause of death worldwide. Despite the
development of novel surgical and therapeutic strategies, 50% of patients relapse after …

Although the chemoprevention and anti-cancer activities of dietary polyphenols have been
evidenced through both in vitro and in vivo studies, most of the human clinical trials were …

Colorectal adenoma (CRA) is a premalignant lesion of colorectal cancer. The current
treatment is surgical resection, but CRA is prone to recurrence, and there is no safe and …