Purpose: Detection of cardiac involvement in Fabry disease (FD) is of high importance for
treatment management. Native T1 mapping especially showed great potential for detection …

Abstract Introduction About 50% of Fabry disease (FD) patients develop cardiac
manifestation, also known as Fabry cardiomyopathy. Beside echocardiography, cardiac …

Background Cardiac involvement is a major contributor of morbidity and mortality in Fabry
disease (FD). Early detection and accurate evaluation of the disease progression is …

Background Cardiac involvement is common and is the leading cause of mortality in Fabry
disease (FD). We explored the association between cardiovascular magnetic resonance …

The aim of this study was to test the hypothesis that in patients with Fabry disease, 2D
speckle-tracking echocardiography (2DSTE) could detect functional myocardial alterations …

Introduction Detecting early cardiac involvement in Fabry disease (FD) is important because
therapy may alter disease progression. Cardiovascular magnetic resonance (CMR) can …

Background: Cardiovascular disease is the most common cause of death among Fabry
disease patients, who carry significantly increased risk for heart failure and sudden cardiac …

Purpose The accumulation of sphingolipids in Fabry's disease (FD) leads to left ventricular
(LV) hypertrophy and shortened T1 in cardiac magnetic resonance (CMR). Early detection of …

Aims Fabry disease (FD) is a multisystemic lysosomal storage disorder caused by a defect in
the alpha-galactosidase A gene that manifests as a phenocopy of hypertrophic …

Background Cardiovascular sequelae represent a leading cause of mortality in Fabry
disease. Early detection of cardiac involvement is therefore a subject of considerable …