Current targeted therapies for the fight against non-small cell lung cancer

LM Mustachio, J Roszik - Pharmaceuticals, 2020 - mdpi.com
Lung cancers contribute to the greatest number of cancer-related deaths worldwide and still
pose challenges in response to current treatment strategies. Non-small cell lung cancer …

Current therapeutic strategies and challenges in NSCLC treatment: A comprehensive review

M Kumar, A Sarkar - Experimental oncology, 2022 - exp-oncology.com.ua
Non-small cell lung cancer (NSCLC) is one of the most lethal malignancies accountings for
nearly 80% of all lung cancer cases diagnosed and causing over one million deaths …

Advanced NSCLC: from cytotoxic systemic chemotherapy to molecularly targeted therapy

T Hoang, JH Schiller - Expert Review of Anticancer Therapy, 2002 - Taylor & Francis
Approximately a third of non-small cell lung cancer patients present with disseminated
disease at the time of diagnosis. For these patients, as well as those with recurrent disease …

New targets for non-small-cell lung cancer therapy

M Alvarez, E Roman, ES Santos… - Expert review of …, 2007 - Taylor & Francis
Lung cancer remains the leading cause of malignancy-related deaths in the USA,
regardless of advances in therapeutic agents. Non-small-cell lung cancer demonstrates …

The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future directions

J Zhong, H Bai, Z Wang, J Duan, W Zhuang… - Frontiers of …, 2023 - Springer
With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC),
expanding the targeted therapeutic options improved the survival and safety. However …

Treatment paradigms in advanced non-small-cell lung cancer.

CE McCoach, K Kelly - Clinical Advances in Hematology and …, 2013 - escholarship.org
Lung cancer is the most common cause of cancer-related death worldwide, owing to its
metastatic spread at the time of diagnosis. As a result, chemotherapy is the standard of care …

Targeted therapy in non-small-cell lung cancer—is it becoming a reality?

F Janku, DJ Stewart, R Kurzrock - Nature reviews Clinical oncology, 2010 - nature.com
Abstract Treatment outcomes in advanced or metastatic non-small-cell lung cancer (NSCLC)
remain unsatisfactory, with low long-term survival rates. Palliative chemotherapy offers a …

Targeted therapy moves to earlier stages of non-small-cell lung cancer: emerging evidence, controversies and future challenges

X Mielgo-Rubio, M Martín, J Remon, O Higuera… - Future …, 2021 - Future Medicine
Lung cancer continues to be the leading cause of cancer mortality and a serious health
problem despite the numerous advances made in the last decade and the rapid advance of …

Advances in chemotherapy in advanced non-small-cell lung cancer

P Maione, A Rossi, PC Sacco… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Lung cancer is the most common cancer in the world today, in terms
of both incidence and mortality. Non-small-cell lung cancer (NSCLC) accounts for about …