Clinical experiences with molecular targeted therapy in lung cancer in C hina

Y Wang, Y Sun - Thoracic Cancer, 2015 - Wiley Online Library
In the past decade, a dramatic shift has been witnessed in cancer therapy in C hina.
Although traditional cytotoxic chemotherapy still remains the treatment of choice for many …

[HTML][HTML] Recent advances in lung cancer: summary of presentations from the 47th annual meeting of the American Society of Clinical Oncology (ASCO) 2011

J Subramanian, SN Waqar, D Morgensztern… - Journal of Thoracic …, 2012 - Elsevier
In the last several years, we have made slow but steady progress in developing new
treatment strategies for patients with lung cancer. The use of molecularly targeted therapy …

Targeted therapy for lung cancer: present and future

C Aggarwal - Annals of palliative medicine, 2014 - apm.amegroups.org
Recent advances in methods of genomic profiling have accelerated our understanding of
the biology of oncologic diseases. Accumulating evidence suggests that both histology and …

[HTML][HTML] Targeted therapy for non-small cell lung cancer

JS Kim, EJ Kang - The Korean Journal of Medicine, 2020 - ekjm.org
Abstract Treatment of progressive non-small cell lung cancer (NSCLC) has advanced
remarkably, due in part to the development of targeted therapies. Several gene alterations …

Oncogenic drivers, targeted therapies, and acquired resistance in non-small-cell lung cancer

A Gower, Y Wang, G Giaccone - Journal of molecular medicine, 2014 - Springer
In the past decade, a shift toward targeted therapies in non-small-cell lung cancer following
molecular profiling has dramatically changed the way advanced adenocarcinoma is treated …

[HTML][HTML] The emerging treatment landscape of advanced non-small cell lung cancer

P Economopoulou, G Mountzios - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
Lung cancer remains the leading cause of cancer related death worldwide. Despite broad
advances in diagnostics and therapy, the five-year overall survival for patients with …

[HTML][HTML] Targeted therapies in early stage NSCLC: hype or hope?

A Friedlaender, A Addeo, A Russo, V Gregorc… - International journal of …, 2020 - mdpi.com
Non-small-cell lung cancer (NSCLC) represents roughly 85% of lung cancers, with an
incidence that increases yearly across the world. The introduction in clinical practice of …

[HTML][HTML] Novel targets, novel treatments: the changing landscape of non-small cell lung cancer

D de Jong, JP Das, H Ma, J Pailey Valiplackal… - Cancers, 2023 - mdpi.com
Simple Summary Non-small cell lung cancer treatment has undergone a revolution in the
past decade owing to the discovery of mutations that drive carcinogenesis and the …

[HTML][HTML] Oncogenic driver mutations in non-small cell lung cancer: Past, present and future

M Chevallier, M Borgeaud, A Addeo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Lung cancer, of which non-small lung cancer is the most common subtype, represents the
leading cause of cancer related-death worldwide. It is now recognized that a significant …

[HTML][HTML] Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer

Z Wang, Y Xing, B Li, X Li, B Liu, Y Wang - Molecular biomedicine, 2022 - Springer
Lung cancer is the leading cause of cancer-related mortality worldwide. The discovery of
tyrosine kinase inhibitors effectively targeting EGFR mutations in lung cancer patients in …