The possible mediatory role of cAMP in the induction of oocyte maturation by luteinizing
hormone (LH) is not yet clear since evidence for both inhibitory and stimulatory actions of the …

The hypothesis that cumulus cells inhibit oocyte maturation by a cAMP-dependent process
was tested (RM Schultz, R. Montgomery, PF Ward-Bailey, and JJ Eppig (1983). Dev. Biol …

The hormone-independent, spontaneous maturation that rat oocytes undergo in vitro can be
inhibited by derivatives of cyclic AMP and inhibitors of cyclic nucleotide phosphodiesterase …

We suggest that cAMP is a key molecule in regulation of oocyte maturation. In the small
follicle, tonic levels of cAMP are continuously transferred to the oocytes to maintain meiotic …

The nature and functions of the chemical signals involved in the acquisition of competence
to resume meiosis, and the maintenance of meiotic arrest in antral follicles are the subjects …

This study was undertaken in order to analyse the role of cyclic AMP (cAMP) in the
stimulatory action of LH on the resumption of oocyte meiosis (oocyte maturation) and …

It is known that dibutyryl cyclic AMP (dbcAMP) and theophylline inhibit the spontaneous
maturation of isolated mouse oocytes. The present study demonstrates that dbcAMP (0.01 …

We have reported that in vitro treatment with follicle-stimulating hormone (FSH) delays by
about 3 h spontaneous meiotic resumption in cumulus cell-enclosed mouse oocytes. In the …

The original model for regulation of oocyte maturation proposed by us in 1978 postulated
that gap junction-mediated transmission of cAMP from the follicle cells to the oocyte inhibits …

The cyclic adenosine monophosphate (cAMP) content of intact oocyte‐cumulus cell
complexes at various times after the induction of oocyte maturation in mice in vivo was …