The gene for spinocerebellar ataxia 7 (SCA7) includes a transcribed, translated CAG tract
that is expanded in SCA7 patients. We have determined expansions in 73 individuals from …

Spinocerebellar ataxia type I (SCAI) is an autosomal dominant neurodegenerative disease
caused by the expansion of a CAG trinucleotide repeat on chromosome 6p. Normal alleles …

Background: Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar
ataxia (ADCA) for which the disease-causing mutation has recently been characterized as …

Sixteen patients from nine Chinese families with spinocerebellar ataxia type 2 (SCA2) were
heterozygous for a CAG repeat expansion in the SCA2 gene containing 37 to 56 repeats …

The autosomal dominant late onset spinocerebellar ataxias (SCAs) are genetically
heterogeneous. Three genes, SCA1 on 6p, SCA2 on 12q and MJD1 on 14q, have been …

Autosomal dominant spinocerebellar ataxias (SCA) are a group of clinically and genetically
heterogeneous neurodegenerative disorders which lead to progressive cerebellar ataxia. A …

Autosomal dominant cerebellar ataxia type 1 (ADCA1) is a clinical and genetic
heterogeneous neurodegenerative disorder which leads to progressive cerebellar ataxia …

Major advances have been made in the understanding of autosomal dominant cerebellar
ataxias since genetic markers came into use in the 1980s. The subsequent mapping of nine …

The most frequent subtype of autosomal dominant inherited spinocerebellar ataxias is
caused by CAG repeat expansions of more than 55 units in the ataxin-3 gene. The clinical …

The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24. 1. A1. 1–
megabase contig in the candidate region was assembled in P1 artificial chromosome and …