MicroRNA‐146a and human disease

L Li, XP Chen, YJ Li - Scandinavian journal of immunology, 2010 - Wiley Online Library
MicroRNAs (MiRNAs) belong to a class of small non‐coding regulatory RNAs that act
through repression of protein expression at post‐transcriptional level and emerge to play …

MiR‐146a in immunity and disease

N Rusca, S Monticelli - Molecular biology international, 2011 - Wiley Online Library
MicroRNAs (miRNAs) are regulatory molecules able to influence all aspects of the biology of
a cell. They have been associated with diseases such as cancer, viral infections, and …

Association of MicroRNA-146a with autoimmune diseases

WD Xu, MM Lu, HF Pan, DQ Ye - Inflammation, 2012 - Springer
MicroRNAs (miRNAs) are a group of approximately 20–22-nucleotide-long non-coding
RNAs that repress target gene expression through mRNA degradation and translation …

A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases

SS Mortazavi-Jahromi, M Aslani, A Mirshafiey - Immunology Letters, 2020 - Elsevier
MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a
length of about 22 nucleotides, which regulate genes expression, through modulating the …

[HTML][HTML] MicroRNA-146a: a dominant, negative regulator of the innate immune response

R Saba, DL Sorensen, SA Booth - Frontiers in immunology, 2014 - frontiersin.org
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that can play critical
roles as regulators of numerous pathways and biological processes including the immune …

Role of miRNA-146a in the regulation of the innate immune response and cancer

AE Williams, MM Perry, SA Moschos… - Biochemical Society …, 2008 - portlandpress.com
In mammalian cells, miRNAs (microRNAs) are the most abundant family of small non-coding
RNAs that regulate mRNA translation through the RNA interference pathway. In general, it …

Altered miR‐146a expression in Sjögren's syndrome and its functional role in innate immunity

KM Pauley, CM Stewart, AE Gauna… - European journal of …, 2011 - Wiley Online Library
Abstract MicroRNAs (miRNAs), small non‐coding RNA molecules that post‐transcriptionally
regulate gene expression, are known to play key roles in regulating immune responses and …

MicroRNA-146a in autoimmunity and innate immune responses

EKL Chan, A Ceribelli, M Satoh - Annals of the rheumatic diseases, 2013 - ard.bmj.com
MicroRNA (miRNA) are approximately 22 nucleotide single-stranded RNA that regulate the
stability of target messenger RNA by selective binding to specific sites at the 3 …

[HTML][HTML] miR-146 and miR-155: two key modulators of immune response and tumor development

U Testa, E Pelosi, G Castelli, C Labbaye - Non-coding RNA, 2017 - mdpi.com
MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …

[HTML][HTML] miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

MP Boldin, KD Taganov, DS Rao, L Yang… - The Journal of …, 2011 - ncbi.nlm.nih.gov
Excessive or inappropriate activation of the immune system can be deleterious to the
organism, warranting multiple molecular mechanisms to control and properly terminate …