A late role for the association of hnRNP A2 with the HIV-1 hnRNP A2 response elements in genomic RNA, Gag, and Vpr localization

V Bériault, JF Clément, K Lévesque, C LeBel… - Journal of Biological …, 2004 - ASBMB
Two cis-acting RNA trafficking sequences (heterogenous ribonucleoprotein A2 (hnRNP A2)-
response elements 1 and 2 or A2RE-1 and A2RE-2) have been identified in HIV-1 vpr and …

RNA trafficking signals in human immunodeficiency virus type 1

AJ Mouland, H Xu, H Cui, W Krueger… - … and cellular biology, 2001 - Taylor & Francis
Intracellular trafficking of retroviral RNAs is a potential mechanism to target viral gene
expression to specific regions of infected cells. Here we show that the human …

Trafficking of HIV‐1 RNA is mediated by heterogeneous nuclear ribonucleoprotein A2 expression and impacts on viral assembly

K Lévesque, M Halvorsen, L Abrahamyan… - Traffic, 2006 - Wiley Online Library
Few details are known about how the human immunodeficiency virus type 1 (HIV‐1)
genomic RNA is trafficked in the cytoplasm. Part of this process is controlled by the activity of …

Human immunodeficiency virus type 1 (HIV-1) induces the cytoplasmic retention of heterogeneous nuclear ribonucleoprotein A1 by disrupting nuclear import …

A Monette, L Ajamian, M López-Lastra… - Journal of Biological …, 2009 - ASBMB
Human immunodeficiency virus type 1 (HIV-1) co-opts host proteins and cellular
machineries to its advantage at every step of the replication cycle. Here we show that HIV-1 …

Depletion of hnRNP A2/B1 overrides the nuclear retention of the HIV-1 genomic RNA

H Gordon, L Ajamian, F Valiente-Echeverrìa… - RNA biology, 2013 - Taylor & Francis
hnRNP A2 is a cellular protein that is important for nucleocytoplasmic and cytosolic
trafficking of the HIV-1 genomic RNA. Both hnRNP A2's interaction with HIV-1 RNA and its …

Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1

I Najera, M Krieg, J Karn - Journal of molecular biology, 1999 - Elsevier
The structural and accessory proteins of human immunodeficiency virus type 1 are
expressed by unspliced or partially spliced mRNAs. Efficient transport of these mRNAs from …

Binding of an RNA trafficking response element to heterogeneous nuclear ribonucleoproteins A1 and A2

J Shan, K Moran-Jones, TP Munro, GJ Kidd… - Journal of Biological …, 2000 - ASBMB
Heterogeneous nuclear ribonucleoprotein (hnRNP) A2 binds a 21-nucleotide myelin basic
protein mRNA response element, the A2RE, and A2RE-like sequences in other localized …

A truncated hnRNP A1 isoform, lacking the RGG-box RNA binding domain, can efficiently regulate HIV-1 splicing and replication

J Jean-Philippe, S Paz, ML Lu, M Caputi - Biochimica et Biophysica Acta …, 2014 - Elsevier
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is one of the most abundant RNA
binding proteins. hnRNP A1 is localized prevalently in the nucleus but it can relocate to the …

hnRNP E1 and E2 have distinct roles in modulating HIV-1 gene expression

K Woolaway, K Asai, A Emili, A Cochrane - Retrovirology, 2007 - Springer
Abstract Pre-mRNA processing, including 5'end capping, splicing, and 3'end cleavage/
polyadenylation, are events coordinated by transcription that can influence the subsequent …

Mutational analysis of a heterogeneous nuclear ribonucleoprotein A2 response element for RNA trafficking

TP Munro, RJ Magee, GJ Kidd, JH Carson… - Journal of Biological …, 1999 - ASBMB
Cytoplasmic transport and localization of mRNA has been reported for a range of oocytes
and somatic cells. The heterogeneous nuclear ribonucleoprotein (hnRNP) A2 response …