rs629301 CELSR2 polymorphism confers a ten-year equivalent risk of critical stenosis assessed by coronary angiography

D Noto, AB Cefalù, N Martinelli, A Giammanco… - Nutrition, Metabolism …, 2021 - Elsevier
Background and aims Novel genetic determinants associated with coronary artery disease
(CAD) have been discovered by genome wide association studies. Variants encompassing …

GW26-e2113 Polymorphisms in the CELSR2-PSRC1-SORT1 are associated with serum lipid traits, the risk of coronary artery disease and ischemic stroke

Y Zhou, Q Yang, R Yin - Journal of the American College of Cardiology, 2015 - jacc.org
Objectives Recent genome-wide association studies (GWAS) have identified CELSR2-
PSRC1-SORT1 variants on chromosome 1p13. 3 associated with CAD and plasma …

[HTML][HTML] CELSR2–PSRC1–SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort

P Arvind, J Nair, S Jambunathan, VV Kakkar… - Journal of …, 2014 - Elsevier
Background Genetic regulation of plasma lipids has been shown to influence the risk of
coronary artery disease (CAD). We analyzed the relationship between rs599839 and …

[HTML][HTML] Association of variants in CELSR2-PSRC1-SORT1 with risk of serum lipid traits, coronary artery disease and ischemic stroke

YJ Zhou, SC Hong, Q Yang, RX Yin… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Recent genome-wide association studies (GWAS) have identified genetic variants
associated with coronary artery disease (CAD), ischemic stroke (IS) and serum lipid traits in …

Association between Genetic Variants of CELSR2-PSRC1-SORT1 and Cardiovascular Diseases: A Systematic Review and Meta-Analysis

RG Castillo-Avila, TB Gonzalez-Castro… - Journal of …, 2023 - mdpi.com
A cluster of three genes CELSR2, PSRC1, and SORT1 has been associated with
cardiovascular diseases. Thus, the aim of this study was (i) to perform a systematic review …

A study of the association of rs12040273 with susceptibility and severity of coronary artery disease in a Chinese Han population

B Yang, S Yan, J Yan, Y Li, MR Khurwolah… - BMC Cardiovascular …, 2018 - Springer
Background The single nucleotide polymorphism (SNP) rs12040273, a variant of UDP-N–
acetylgalactosamine, polypeptide GalNAc-transferase 2, has recently been reported to be …

The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum …

NJ Samani, PS Braund, J Erdmann, A Götz… - Journal of molecular …, 2008 - Springer
Through genome-wide association studies, we have recently identified seven novel loci that
confer a substantial increase in risk for coronary artery disease (CAD). Elucidating the …

The association between serum LDL cholesterol and genetic variation in chromosomal locus 1p13. 3 among coronary artery disease patients

NM Rizk, A El-Menyar, H Egue… - BioMed Research …, 2015 - Wiley Online Library
Background. Several polymorphisms of a locus on chromosome 1p13. 3 have a significant
effect on low‐density lipoprotein cholesterol (LDL‐C), atherosclerosis, and acute coronary …

Cholesterol associated genetic risk score and acute coronary syndrome in Czech males

JA Hubacek, V Adamkova, V Lanska, V Staněk… - Molecular Biology …, 2024 - Springer
Background Despite a general decline in mean levels across populations, LDL-cholesterol
levels remain a major risk factor for acute coronary syndrome (ACS). The APOB, LDL-R …

There is an association between a genetic polymorphism in the ZNF259 gene involved in lipid metabolism and coronary artery disease

SR Mirhafez, A Avan, S Khatamianfar, F Ghasemi… - Gene, 2019 - Elsevier
Background Recent genome-wide association studies (GWAS) have identified several
genetic variants that influence the risk of dyslipidemia and coronary artery disease (CAD). In …