Development and validation of a novel immune-related prognostic model in hepatocellular carcinoma

Z Wang, J Zhu, Y Liu, C Liu, W Wang, F Chen… - Journal of translational …, 2020 - Springer
Background Growing evidence has suggested that immune-related genes play crucial roles
in the development and progression of hepatocellular carcinoma (HCC). Nevertheless, the …

Seven immune‐related genes prognostic power and correlation with tumor‐infiltrating immune cells in hepatocellular carcinoma

T Liu, H Wu, J Qi, C Qin, Q Zhu - Cancer Medicine, 2020 - Wiley Online Library
Background Given poor prognosis and the lack of efficient therapy for advanced
hepatocellular carcinoma, immunotherapy has emerged as an increasingly important role …

Identification of a prognostic and therapeutic immune signature associated with hepatocellular carcinoma

Y Peng, C Liu, M Li, W Li, M Zhang, X Jiang… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most prevalent and inflammation-
associated cancers. The tumor microenvironment (TME) plays an essential role in HCC …

A signature of 33 immune‐related gene pairs predicts clinical outcome in hepatocellular carcinoma

XY Sun, SZ Yu, HP Zhang, J Li, WZ Guo… - Cancer …, 2020 - Wiley Online Library
Objective Hepatocellular carcinoma (HCC) has become the second most common tumor
type that contributes to cancer‐related death worldwide. The study aimed to establish a …

[HTML][HTML] An immunogenomic signature for molecular classification in hepatocellular carcinoma

W Zhuang, H Sun, S Zhang, Y Zhou, W Weng… - … Therapy-Nucleic Acids, 2021 - cell.com
Immunity plays an important role in tumor development. In this study, we aimed to
investigate molecular classification and its prognostic value in hepatocellular carcinoma …

An inflammatory response-related gene signature can impact the immune status and predict the prognosis of hepatocellular carcinoma

Z Lin, Q Xu, D Miao, F Yu - Frontiers in oncology, 2021 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, which
makes the prognostic prediction challenging. As part of the active cross-talk between the …

An immune-related gene signature for predicting survival and immunotherapy efficacy in hepatocellular carcinoma

Y Dai, W Qiang, K Lin, Y Gui, X Lan, D Wang - Cancer Immunology …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) ranks the fourth in terms of cancer-related
mortality globally. Herein, in this research, we attempted to develop a novel immune-related …

Identification and validation of immune‐related gene prognostic signature for hepatocellular carcinoma

W Chen, M Ou, D Tang, Y Dai… - Journal of immunology …, 2020 - Wiley Online Library
Immune‐related genes (IRGs) have been identified as critical drivers of the initiation and
progression of hepatocellular carcinoma (HCC). This study is aimed at constructing an IRG …

A novel prognostic index of hepatocellular carcinoma based on immunogenomic landscape analysis

H Xiao, B Wang, HX Xiong, JF Guan… - Journal of cellular …, 2021 - Wiley Online Library
Abstract Changes in immune responses to hepatocellular carcinoma (HCC) are closely
related to the occurrence, development, and prognosis of this disease. Exploring the role of …

Model based on five tumour immune microenvironment-related genes for predicting hepatocellular carcinoma immunotherapy outcomes

X Gu, J Guan, J Xu, Q Zheng, C Chen, Q Yang… - Journal of translational …, 2021 - Springer
Background Although the tumour immune microenvironment is known to significantly
influence immunotherapy outcomes, its association with changes in gene expression …