Molecular network of neuronal autophagy in the pathophysiology and treatment of depression
J Jia, W Le - Neuroscience bulletin, 2015 - Springer
Major depressive disorder (MDD) is a complicated multifactorial induced disease,
characterized by depressed mood, anhedonia, fatigue, and altered cognitive function …
characterized by depressed mood, anhedonia, fatigue, and altered cognitive function …
[HTML][HTML] Targeting autophagy to counteract neuroinflammation: a novel antidepressant strategy
H Gan, Q Ma, W Hao, N Yang, ZS Chen, L Deng… - Pharmacological …, 2024 - Elsevier
Depression is a common disease that affects physical and mental health and imposes a
considerable burden on afflicted individuals and their families worldwide. Depression is …
considerable burden on afflicted individuals and their families worldwide. Depression is …
Is there a role of autophagy in depression and antidepressant action?
NC Gassen, T Rein - Frontiers in Psychiatry, 2019 - frontiersin.org
Autophagy has been recognized as evolutionary conserved intracellular pathway that
ensures energy, organelle, and protein homeostasis through lysosomal degradation of …
ensures energy, organelle, and protein homeostasis through lysosomal degradation of …
[HTML][HTML] In vitro methods in autophagy research: Applications in neurodegenerative diseases and mood disorders
DI Sánchez-Vidaña, J Li, S Abokyi… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Autophagy is a conserved physiological intracellular mechanism responsible
for the degradation and recycling of cytoplasmic constituents (eg, damaged organelles, and …
for the degradation and recycling of cytoplasmic constituents (eg, damaged organelles, and …
Is autophagy involved in the diverse effects of antidepressants?
T Rein - Cells, 2019 - mdpi.com
Autophagy has received increased attention as a conserved process governing cellular
energy and protein homeostasis that is thus relevant in a range of physiological and …
energy and protein homeostasis that is thus relevant in a range of physiological and …
Stress and signaling pathways regulating autophagy: from behavioral models to psychiatric disorders
Autophagy is a process of degradation and recycling of cytoplasmatic components by the
lysosomes. In the central nervous system (CNS), autophagy is involved in cell surveillance …
lysosomes. In the central nervous system (CNS), autophagy is involved in cell surveillance …
Exploring the role of autophagy dysfunction in neurodegenerative disorders
Autophagy is a catabolic pathway by which misfolded proteins or damaged organelles are
engulfed by autophagosomes and then transported to lysosomes for degradation. Recently …
engulfed by autophagosomes and then transported to lysosomes for degradation. Recently …
[HTML][HTML] Pharmacological modulation of autophagy for Alzheimer's disease therapy: opportunities and obstacles
Alzheimer's disease (AD) is a prevalent and deleterious neurodegenerative disorder
characterized by an irreversible and progressive impairment of cognitive abilities as well as …
characterized by an irreversible and progressive impairment of cognitive abilities as well as …
Autophagy modulation for Alzheimer's disease therapy
XC Zhu, JT Yu, T Jiang, L Tan - Molecular neurobiology, 2013 - Springer
Autophagy is an essential and conserved lysosomal degradation pathway that controls the
quality of cytoplasm by eliminating the intracellular aggregated proteins and damaged …
quality of cytoplasm by eliminating the intracellular aggregated proteins and damaged …
Autophagy and Alzheimer's disease: from molecular mechanisms to therapeutic implications
MS Uddin, A Stachowiak, AA Mamun… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of progressive dementia in the elderly.
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …