[HTML][HTML] Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr−/− mouse model of western …

CM Depner, KA Philbrick, DB Jump - The Journal of nutrition, 2013 - Elsevier
The incidence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis
(NASH) has increased in parallel with the incidence of obesity. While both NAFLD and …

Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice

KA Lytle, CP Wong, DB Jump - PloS one, 2017 - journals.plos.org
Background Nonalcoholic fatty liver disease (NAFLD) is a major public health concern in
western societies. Nonalcoholic steatohepatitis (NASH), the progressive form of NAFLD, is …

Different effects of eicosapentaenoic and docosahexaenoic acids on atherogenic high-fat diet-induced non-alcoholic fatty liver disease in mice

N Suzuki-Kemuriyama, T Matsuzaka, M Kuba, H Ohno… - PloS one, 2016 - journals.plos.org
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome,
can progress to steatohepatitis (NASH) and advanced liver damage, such as that from liver …

[HTML][HTML] Menhaden oil decreases high-fat diet–induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr−/− mice

CM Depner, M Torres-Gonzalez, S Tripathy… - The Journal of …, 2012 - Elsevier
The frequency of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis
(NASH) has increased in parallel with obesity in the United States. NASH is progressive and …

A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

CM Depner, MG Traber, G Bobe, E Kensicki… - PLoS …, 2013 - journals.plos.org
Background Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty
liver disease and a risk factor for cirrhosis, hepatocellular carcinoma and liver failure …

An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high‐fat “Western‐type” diet in mice

E Jurado‐Ruiz, LM Varela, A Luque… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope We evaluated the protective effect of extra virgin olive oil (EVOO) in high‐fat diets
(HFDs) on the inflammatory response and liver damage in a nonalcoholic fatty liver disease …

Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis

F Takayama, K Nakamoto, N Totani… - Journal of Oleo …, 2010 - jstage.jst.go.jp
Docosahexaenoic acid (DHA) regulates the lipid metabolism and inflammation that is
closely associated with oxidative stress. The present study investigated the effects of DHA …

Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr−/− mice

DB Jump, CM Depner, S Tripathy… - Proceedings of the …, 2016 - cambridge.org
The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased in parallel with
central obesity and is now the most common chronic liver disease in developed countries …

[HTML][HTML] Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer

DB Jump, CM Depner, S Tripathy, KA Lytle - Advances in Nutrition, 2015 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity, and
its prevalence is anticipated to increase as the obesity epidemic remains unabated. NAFLD …

[PDF][PDF] Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

K Wouters, PJ van Gorp, V Bieghs, MJ Gijbels… - …, 2008 - Wiley Online Library
Nonalcoholic steatohepatitis (NASH) involves liver lipid accumulation (steatosis) combined
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …