Drug delivery through the skin by transdermal patches has a long history. Subsequent
growth of transdermal science proved prominent utility of transdermal systems meant for …

In many clinical applications, the transdermal route is used as an alternative approach to
avoid the significant limitations associated with oral drug delivery. There is a long history for …

A microneedle (MN) is a micron-sized needle with a height of 10–2000 μm and a width of 10–
50 μm, which can penetrate through the epidermis layer to dermal tissue directly without …

Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …

[Frontiers in Bioscience 13, 1711-1715, January 1, 2008] 1711 Microneedles for transdermal
drug delivery: a minireview Jo Vande Page 1 [Frontiers in Bioscience 13, 1711-1715, January …

Introduction: The most conventional drug delivery systems exist with limitations such as drug
degradation, toxicity and low bioavailability. Also, hypodermic injections can cause pain …

The most widely used methods for transdermal administration of the drugs are hypodermic
needles, topical creams, and transdermal patches. The effect of most of the therapeutic …

As non-toxic, biodegradable, biocompatible materials, the polymeric microneedles have a
great significance in terms of delivering therapeutic drug molecules through the skin. They …

In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …