Microneedles have been used for the dermal and transdermal delivery of a broad range of
drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and …

Microneedles were first conceptualized for drug delivery many decades ago, overcoming the
shortages and preserving the advantages of hypodermic needle and conventional …

Human skin is made up of multiple layers and is designed to protect the human body. The
stratum corneum (SC), specifically, is a keratinized layer of skin through which molecules …

Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

Transdermal drug delivery is a viable and clinically proven route of administration. This route
specifically requires overcoming the mechanical barrier provided by the Stratum Corneum of …

In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

In many clinical applications, the transdermal route is used as an alternative approach to
avoid the significant limitations associated with oral drug delivery. There is a long history for …

Transdermal devices are used to deliver drugs through the skin. However, limitations such
as molecular weight and hydrophilicity of the molecules prevent its wider use. Microneedle …

[Frontiers in Bioscience 13, 1711-1715, January 1, 2008] 1711 Microneedles for transdermal
drug delivery: a minireview Jo Vande Page 1 [Frontiers in Bioscience 13, 1711-1715, January …