Elucidation of tumor-stromal heterogeneity and the ligand-receptor interactome by single-cell transcriptomics in real-world pancreatic cancer biopsies
Purpose: Precision medicine approaches in pancreatic ductal adenocarcinoma (PDAC) are
imperative for improving disease outcomes. With molecular subtypes of PDAC gaining …
imperative for improving disease outcomes. With molecular subtypes of PDAC gaining …
Machine learning and network analyses reveal disease subtypes of pancreatic cancer and their molecular characteristics
Given that the biological processes governing the oncogenesis of pancreatic cancers could
present useful therapeutic targets, there is a pressing need to molecularly distinguish …
present useful therapeutic targets, there is a pressing need to molecularly distinguish …
Transcriptomic profiling of tumor aggressiveness in sporadic nonfunctioning pancreatic neuroendocrine neoplasms
SP Haugvik, D Vodák, L Haugom, E Hovig… - Pancreas, 2016 - journals.lww.com
Objectives The aim of the study was to compare RNA sequencing data of sporadic
nonfunctioning pancreatic neuroendocrine neoplasms (PNENs) to identify gene expression …
nonfunctioning pancreatic neuroendocrine neoplasms (PNENs) to identify gene expression …
Author Correction: Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas
In the version of this article initially published, Fig. 5d reported the analysis of 183 pancreatic
ductal adenocarcinoma (PDAC) RNA-seq transcriptomes from The Cancer Genome Atlas …
ductal adenocarcinoma (PDAC) RNA-seq transcriptomes from The Cancer Genome Atlas …
[HTML][HTML] Identification and characterization of the gene expression profiles for protein coding and non-coding RNAs of pancreatic ductal adenocarcinomas
ML Gutiérrez, L Corchete, C Teodosio… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Significant advances have been achieved in recent years in the identification of the genetic
and the molecular alterations of pancreatic ductal adenocarcinoma (PDAC). Despite this, at …
and the molecular alterations of pancreatic ductal adenocarcinoma (PDAC). Despite this, at …
Application of multiomics sequencing and advances in the molecular mechanisms of pancreatic neuroendocrine neoplasms
R Jiang, X Hong, Y Zhao, W Wu - Cancer Letters, 2021 - Elsevier
The incidence of pancreatic neuroendocrine neoplasms (PanNENs) has gradually
increased. PanNENs comprise two subtypes with different clinical manifestations and …
increased. PanNENs comprise two subtypes with different clinical manifestations and …
[HTML][HTML] PO-277 single-cell RNA-seq analysis of human pancreatic ductal adenocarcinoma
ABSTRACT Introduction Pancreatic Ductal Adenomcarcinoma (PDAC) is one of the most
lethal forms of cancer with a five-year survival rate of 8%. Genetic alterations such as …
lethal forms of cancer with a five-year survival rate of 8%. Genetic alterations such as …
Three distinct stroma types in human pancreatic cancer identified by image analysis of fibroblast subpopulations and collagen
Y Ogawa, Y Masugi, T Abe, K Yamazaki, A Ueno… - Clinical Cancer …, 2021 - AACR
Purpose: Cancer-associated fibroblasts have emerged to be highly heterogenous and can
play multifaceted roles in dictating pancreatic ductal adenocarcinoma (PDAC) progression …
play multifaceted roles in dictating pancreatic ductal adenocarcinoma (PDAC) progression …
Cross-dataset single-cell analysis identifies temporal alterations in cell populations of primary pancreatic tumor and liver metastasis
D Yang, R Moniruzzaman, H Wang, H Wang, Y Chen - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer has a unique desmoplastic tumor microenvironment
composed of various cell populations. However, the direct comparison of cell population …
composed of various cell populations. However, the direct comparison of cell population …
Novel stromal biomarker screening in pancreatic cancer patients using the in vitro cancer-stromal interaction model
Y Nishida, AK Nagatsuma, M Kojima, N Gotohda… - BMC …, 2020 - Springer
Background Stromal fibroblasts associated with pancreatic ductal adenocarcinoma (PDAC)
play an important role in tumor progression through interactions with cancer cells. Our …
play an important role in tumor progression through interactions with cancer cells. Our …