The aim of biomarkers is to identify patients most likely to benefit from a therapeutic strategy.
Pancreatic neuroendocrine tumors are rare neoplasms that arise in the endocrine tissues of …

Abstract Pancreatic Neuroendocrine Neoplasms (PanNENs) comprise a rare and
heterogeneous group of tumors derived from neuroendocrine cells of the pancreas. Despite …

Neuroendocrine tumors (NETs) comprise a group of complex heterogeneous and
increasingly prevalent neoplasms. They arise from diverse body regions, share derivation …

Cancer-associated fibroblasts (CAFs) play an important role in a variety of cancers.
However, the role of tumor stroma in nonfunctional pancreatic neuroendocrine tumors (NF …

Simple Summary Rapidly growing neuroendocrine neoplasms (NEN) often defy easy
classification by the pathologist. Machine learning approaches can improve the …

Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

We read with great interest the recent study by Sinn et al (2014) that demonstrated
significantly increased a-smooth muscle actin (a-SMA) expression in pancreatic cancer …

Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α-
or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not …

Seeking to assess the representative and instructive value of an engineered mouse model
of pancreatic neuroendocrine tumors (PanNET) for its cognate human cancer, we profiled …

Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest
malignancies in the world, for which the mortality is almost as high as the disease incidence …