Anhedonia, a core symptom of Major Depressive Disorder (MDD), is predictive of
antidepressant non-response. In contrast to the definition of anhedonia as a “loss of …

Anhedonia, the decreased capacity to experience pleasure, is a defining symptom of
unipolar major depressive disorder (MDD). This review summarizes definitions and …

The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

Anhedonia, a diminished or lack of ability to experience and anticipate pleasure represents
a core psychiatric symptom in depression. Current clinician assessment of anhedonia is …

Anhedonia or inability to experience pleasure not only is a core symptom of major
depressive disorder (MDD), but also is identified as an important component of the positive …

BACKGROUND: Anhedonia, the inability to experience pleasure, is a major endophenotype
of depression. In addition to this, it is an important clinical feature of schizophrenia and …

Background Anhedonia represents a core symptom of major depression and may be a
potential marker for melancholia. However, current understanding of this construct in …

There is an increasing heavy disease burden of major depressive disorder (MDD) globally.
Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose …

Importance Anhedonia, a reduced capacity for pleasure, is described for many psychiatric
and neurologic conditions. However, a decade after the Research Domain Criteria launch …

Anhedonia is a core symptom of major depressive disorder (MDD), the neurobiological
mechanisms of which remain poorly understood. Despite decades of speculation regarding …