Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

CR Powell, KM Dillon, JB Matson - Biochemical pharmacology, 2018 - Elsevier
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

H2S Donors and Their Use in Medicinal Chemistry

E Magli, E Perissutti, V Santagada, G Caliendo… - Biomolecules, 2021 - mdpi.com
Hydrogen sulfide (H2S) is a ubiquitous gaseous signaling molecule that has an important
role in many physiological and pathological processes in mammalian tissues, with the same …

Trends in H2S-Donors Chemistry and Their Effects in Cardiovascular Diseases

A Corvino, F Frecentese, E Magli, E Perissutti… - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous gasotransmitter recently emerged as an
important regulatory mediator of numerous human cell functions in health and in disease. In …

Hydrogen sulfide donors in research and drug development

ZJ Song, MY Ng, ZW Lee, W Dai, T Hagen… - …, 2014 - pubs.rsc.org
Hydrogen sulfide (H2S) has recently emerged as an important biological gasomediator as a
result of numerous insightful studies. The use of H2S releasing compounds has attracted …

Natural products containing hydrogen sulfide releasing moieties

MD Pluth, TS Bailey, MD Hammers, MD Hartle… - Synlett, 2015 - thieme-connect.com
Hydrogen sulfide (H 2 S) is now recognized as an important biological molecule that plays
diverse roles in various (patho) physiological conditions. Endogenous H 2 S, or its …

Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues

Y Zheng, B Yu, LK De La Cruz… - Medicinal Research …, 2018 - Wiley Online Library
Abstract Hydrogen sulfide (H2S), together with nitric oxide (NO) and carbon monoxide (CO),
belongs to the gasotransmitter family and plays important roles in mammals as a signaling …

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

M Whiteman, S Le Trionnaire, M Chopra, B Fox… - Clinical …, 2011 - portlandpress.com
H2S (hydrogen sulfide) is a well known and pungent gas recently discovered to be
synthesized enzymatically in mammalian and human tissues. In a relatively short period of …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Synthesis and Biological Effects of Hydrogen Sulfide (H2S): Development of H2S-Releasing Drugs as Pharmaceuticals

G Caliendo, G Cirino, V Santagada… - Journal of medicinal …, 2010 - ACS Publications
Gaseous transmitters are a growing family of regulatory molecules involved in multilevel
regulation of physiological and pathological functions in mammalian tissues. 1 Hydrogen …