Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huai Hua San against ulcerative …

J Liu, J Liu, X Tong, W Peng, S Wei, T Sun… - Drug Design …, 2021 - Taylor & Francis
Background Huai Hua San (HHS), a famous Traditional Chinese Medicine (TCM) formula,
has been widely applied in treating ulcerative colitis (UC). However, the interaction of …

[HTML][HTML] Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis

Y Wu, X Liu, G Li - Scientific reports, 2022 - nature.com
Huangqin decoction (HQD) is a Traditional Chinese Medicine formula for ulcerative colitis.
However, the pharmacology and molecular mechanism of HQD on ulcerative colitis is still …

Based on network pharmacology to explore the molecular targets and mechanisms of Gegen Qinlian decoction for the treatment of ulcerative colitis

M Wei, H Li, Q Li, Y Qiao, Q Ma, R Xie… - BioMed Research …, 2020 - Wiley Online Library
Background. Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for
the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target …

[HTML][HTML] Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang

J Jin, B Chen, X Zhan, Z Zhou, H Liu, Y Dong - PLoS One, 2021 - journals.plos.org
Background and objective We aimed to predict the targets and signal pathways of Xiao-Chai-
Hu-Tang (XCHT) in the treatment of colorectal cancer (CRC) based on network …

Network pharmacology-based prediction and verification of the active ingredients and potential targets of zuojinwan for treating colorectal cancer

S Huang, Z Zhang, W Li, F Kong, P Yi… - Drug Design …, 2020 - Taylor & Francis
Background Zuojinwan (ZJW), a famous Chinese medicine formula, has been widely used
to treat colorectal cancer (CRC). However, its bioactive compounds, potential targets, and …

Network pharmacology and pharmacokinetics integrated strategy to investigate the pharmacological mechanism of Xianglian pill on ulcerative colitis

CS Liu, T Xia, ZY Luo, YY Wu, YN Hu, FL Chen… - Phytomedicine, 2021 - Elsevier
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with high
morbidity, which leads to poor quality of life. The Xianglian pill (XLP) is a classical Chinese …

[HTML][HTML] Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking

S Gu, Y Xue, Y Gao, S Shen, Y Zhang, K Chen, S Xue… - Scientific reports, 2020 - nature.com
Oral administration of indigo naturalis (IN) can induce remission in ulcerative colitis (UC);
however, the underlying mechanism remains unknown. The main active components and …

Exploration of the mechanism of Zisheng Shenqi decoction against gout arthritis using network pharmacology

WH Li, JR Han, PP Ren, Y Xie, DY Jiang - Computational biology and …, 2021 - Elsevier
Background In this study, the network pharmacological methods were used to predict the
target of effective components of compounds in Zisheng Shenqi Decoction (ZSD, or …

[HTML][HTML] Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis

G Yu, W Wang, X Wang, M Xu, L Zhang, L Ding… - … and alternative medicine, 2018 - Springer
Background Zuojinwan (ZJW), a classic herbal formula, has been extensively used to treat
gastric symptoms in clinical practice in China for centuries. However, the pharmacological …

Troxerutin improves dextran sulfate sodium-induced ulcerative colitis in mice

X Wang, Y Gao, L Wang, D Yang, W Bu… - Journal of agricultural …, 2021 - ACS Publications
Screening potential compounds for improving ulcerative colitis (UC) from clinical medication
is an effective strategy for drug repurposing. We applied bioinformatics and network …