Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism
A Ciullo, L Li, C Li, K Tsi, C Farrell… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Extracellular vesicles (EVs) secreted by cardiosphere-
derived cells exert immunomodulatory effects through the transmission of small non-coding …
derived cells exert immunomodulatory effects through the transmission of small non-coding …
Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion
Cardiosphere‐derived cells (CDC s) reduce myocardial infarct size via secreted
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …
microRNA‐454‐mediated NEDD4‐2/TrkA/cAMP axis in heart failure: Mechanisms and cardioprotective implications
Y Wang, W Pan, X Bai, X Wang… - Journal of cellular and …, 2021 - Wiley Online Library
The current study aimed to investigate the mechanism by which miR‐454 influences the
progression of heart failure (HF) in relation to the neural precursor cell expressed …
progression of heart failure (HF) in relation to the neural precursor cell expressed …
Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair
Aims Epicardium and epicardium-derived cells are critical players in myocardial fibrosis.
Mesenchymal stem cell–derived extracellular vesicles (EVs) have been studied for cardiac …
Mesenchymal stem cell–derived extracellular vesicles (EVs) have been studied for cardiac …
MicroRNA-221/222 mediates ADSC-exosome-induced cardioprotection against ischemia/reperfusion by targeting PUMA and ETS-1
TC Lai, TL Lee, YC Chang, YC Chen, SR Lin… - Frontiers in Cell and …, 2020 - frontiersin.org
Cardiovascular disease is a major health problem in industrialized and developing countries
and is the leading cause of death and disability. Myocardial ischemia/reperfusion (I/R) …
and is the leading cause of death and disability. Myocardial ischemia/reperfusion (I/R) …
[HTML][HTML] Long noncoding RNA LUCAT1 enhances the survival and therapeutic effects of mesenchymal stromal cells post-myocardial infarction
Y Tao, Q Liu, R Wu, C Xiao, C Ni, K Wang, W Hu… - … Therapy-Nucleic Acids, 2022 - cell.com
Mesenchymal stromal cell (MSC) transplantation has been a promising therapeutic strategy
for repairing heart tissues post-myocardial infarction (MI). Nevertheless, its therapeutic …
for repairing heart tissues post-myocardial infarction (MI). Nevertheless, its therapeutic …
CXCR4-overexpressed exosomes from cardiosphere-derived cells attenuate myocardial ischemia/reperfusion injury by transferring miRNA to macrophages and …
Y Ma, M Su, W Qian, Y Xuan, T Chen… - Cellular and Molecular …, 2023 - cellmolbiol.org
Cardiosphere-derived cells (CDCs) are emerging as ideal candidates for managing cardiac
inflammation, albeit with some limitations. Recent literatures have indicated that exosomes …
inflammation, albeit with some limitations. Recent literatures have indicated that exosomes …
Mesenchymal stem cells-derived extracellular vesicles-shuttled microRNA-223-3p suppress lipopolysaccharide-induced cardiac inflammation, pyroptosis, and …
L Pan, B Yan, J Zhang, P Zhao, Y Jing, J Yu… - International …, 2022 - Elsevier
Abstract Introduction Mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs)
possess therapeutical potentials in cardiac disorders. We probed into the mechanisms of …
possess therapeutical potentials in cardiac disorders. We probed into the mechanisms of …
The BMSC-derived exosomal lncRNA Mir9-3hg suppresses cardiomyocyte ferroptosis in ischemia-reperfusion mice via the Pum2/PRDX6 axis
JK Zhang, Z Zhang, ZA Guo, Y Fu, XJ Chen… - Nutrition, Metabolism …, 2022 - Elsevier
Background and aims The exosomal long noncoding RNAs (lncRNAs) have been reported
to have cardioprotective effects on ischemia-reperfusion (I/R) injury by hindering ferroptosis …
to have cardioprotective effects on ischemia-reperfusion (I/R) injury by hindering ferroptosis …
Mesenchymal stem cell-derived exosomal microRNA-182-5p alleviates myocardial ischemia/reperfusion injury by targeting GSDMD in mice
R Yue, S Lu, Y Luo, J Zeng, H Liang, D Qin… - Cell death …, 2022 - nature.com
Recent evidence indicates that exosomes derived from mesenchymal stem cells (MSCs)
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …