A review of estrogen receptor/androgen receptor genomics in male breast cancer.

TM Severson, W Zwart - Endocrine-related cancer, 2017 - europepmc.org
Male breast cancer is a rare disease, of which little is known. In contrast to female breast
cancer, the very vast majority of all cases are positive for estrogen receptor alpha (ERα) …

Nuclear and flow cytometric characteristics associated with overexpression of the c-erbB-2 oncoprotein in breast carcinoma

DN Poller, M Galea, D Pearson, J Bell… - Breast cancer research …, 1991 - Springer
The overexpression of the c-erbB-2 oncoprotein is now thought by most authors to be
associated with adverse prognosis in breast carcinoma. In this study, we investigate the …

C-erbB-2, p53, and nm23 gene product expression in breast cancer in young women: immunohistochemical analysis and clinicopathologic correlation

P Bertheau, SM Steinberg, MJ Merino - Human pathology, 1998 - Elsevier
We studied c-erbB-2, p53, and nm23 gene products in 112 primary breast carcinomas. Fifty
patients were aged 35 years or younger, and 62 were aged 36 to 50. Clinicopathological …

Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer

MD Planas-Silva, RD Bruggeman, RT Grenko… - … and molecular pathology, 2007 - Elsevier
The aim of this study was to identify molecules involved in the proliferation and survival of
recurrent estrogen receptor (ER)-positive breast cancer at the site of metastasis. Most …

Prospective studies of p53 and c-erbB-2 expression in relation to clinicopathological parameters of human ductal breast cancer in the second stage of clinical …

M Bebenek, JK Bar, A Harlozinska… - Anticancer research, 1998 - europepmc.org
Background The association between p53 and c-erbB-2 overexpression relation to ER
status in ductal breast carcinoma is still unclear. Our aim was investigate the prognostic …

Evaluation of estrogen receptor α and β and progesterone receptor expression and correlation with clinicopathologic factors and proliferative marker Ki-67 in breast …

FE Rosa, JRF Caldeira, J Felipes, FB Bertonha… - Human pathology, 2008 - Elsevier
To elucidate the molecular profile of hormonal steroid receptor status, we analyzed ER-α,
ER-β, and PGR mRNA and protein expression in 80 breast carcinomas using reverse …

c‐erbB‐2 and ras expression levels in breast cancer are correlated and show a co‐operative association with unfavorable clinical outcome

C Dati, R Muraca, O Tazartes… - … journal of cancer, 1991 - Wiley Online Library
Abstract c‐erbB‐2 and ras expression was measured on tumor extracts from 132 human
primary breast carcinomas, by immunoblotting analysis. Expression of the c‐erbB‐2 …

Expression of ras p21, p53 and c-erbB-2 in advanced breast cancer and response to first line hormonal therapy

SG Archer, A Eliopoulos, D Spandidos… - British journal of …, 1995 - nature.com
Several oncogenes and tumour-suppressor genes have been identified that may have an
important role in the development of human breast carcinoma. Furthermore, some of these …

Estrogen receptor β is coexpressed with ERα and PR and associated with nodal status, grade, and proliferation rate in breast cancer

TAH Järvinen, M Pelto-Huikko, K Holli, J Isola - The American journal of …, 2000 - Elsevier
The role of estrogen (ER) and progesterone receptors (PR) in breast cancer is well
established. Identification of the second human estrogen receptor, the estrogen receptor β …

Correlations of cell cycle regulators (p53, p21, pRb and mdm2) and c‐erbB‐2 with biological markers of proliferation and overall survival in breast cancer

AE Pinto, S André, C Laranjeira, J Soares - Pathology, 2005 - Taylor & Francis
Aim: The biological impact of cell cycle regulatory proteins on breast cancer progression is
widely recognised, although mostly unclear. The aim of this preliminary study was to …