Valsartan and atenolol in patients with severe essential hypertension

R Cifkova, J Peleška, J Hradec, H Rosolova… - Journal of human …, 1998 - nature.com
The aim of this study was to evaluate the efficacy and tolerability of valsartan, a new
angiotensin II receptor antagonist, versus atenolol in the treatment of severe primary …

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril

NJ Holwerda, R Fogari, P Angeli… - Journal of …, 1996 - journals.lww.com
Objective: To compare the antihypertensive efficacy and systemic tolerability of valsartan, a
new angiotensin II receptor antagonist, with placebo and with an angiotensin converting …

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme …

HR Black, A Graff, D Shute, R Stoltz, D Ruff… - Journal of Human …, 1997 - nature.com
Objective: To compare the efficacy, safety and tolerability of valsartan to an angiotensin-
converting enzyme (ACE) inhibitor, lisinopril, and placebo in patients with mild-to-moderate …

The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension

S Oparil, S Dyke, F Harris, J Kief, D James, A Hester… - Clinical …, 1996 - Elsevier
A multicenter, randomized, placebo-controlled, double-masked, parallel-group study was
performed to compare the efficacy and safety of valsartan 20, 80, 160, and 320 mg with …

Evaluation of the dose response with valsartan and valsartan/hydrochlorothiazide in patients with essential hypertension

MR Weir, N Crikelair, D Levy, R Rocha… - The Journal of …, 2007 - Wiley Online Library
This patient data meta‐analysis included 9 randomized, double‐blind, placebo‐controlled
trials (N= 4278) of once‐daily valsartan 80, 160, or 320 mg or valsartan/hydrochlorothiazide …

Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: data from a multicenter, randomized, double-blind, 12-week trial

WJ Elliott, DA Calhoun, PT DeLucca, LP Gazdick… - Clinical …, 2001 - Elsevier
Background: Losartan, the first of the angiotensin II receptor blockers (ARBs) to be
introduced, has been studied extensively in comparison with other classes of …

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared to hydrochlorothiazide

G Hegner, G Faust, F Freytag, S Meilenbrock… - European journal of …, 1997 - Springer
Objective: To compare the antihypertensive efficacy of a new angiotensin II antagonist,
valsartan, with a reference therapy, hydrochlorothiazide (HCTZ). Methods: In this double …

Dose-response efficacy of valsartan, a new angiotensin II receptor blocker

JL Pool, R Glazer, YT Chiang, M Gatlin - Journal of human hypertension, 1999 - nature.com
Objective: To study the efficacy and tolerability of a range of valsartan doses in patients with
mild-to-moderate hypertension. Design: 122 adult out-patients were randomised in equal …

Efficacy and tolerability of valsartan in combination with hydrochlorothiazide in essential hypertension

W Dallas Hall, R Montoro, T Littlejohn, A Jain… - Clinical drug …, 1998 - Springer
Objective: This study compared the efficacy and tolerability of two combination regimens of
valsartan and hydrochlorothiazide (HCTZ) with valsartan monotherapy in patients with …

Long-term efficacy, safety, and tolerability of valsartan and hydrochlorothiazide in patients with essential hypertension

SG Chrysant, DG Womboldt, N Feliciano… - Current therapeutic …, 1998 - Elsevier
The long-term safety data on angiotensin II receptor blockers in combination with thiazide
diuretics are limited. The present study reports on the long-term efficacy, safety, and …