Enalapril as a first-step agent in essential hypertension: a comparative study with atenolol.

D Edmonds, P Greminger, R Locher… - … : Official Journal of the …, 1986 - europepmc.org
The aim of the present double-blind crossover study was to compare the antihypertensive
efficacy and tolerability of enalapril and atenolol in 48 patients with mild to moderate …

Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy

S Oparil, T Giles, EO Ofili, B Pitt, Y Seifu… - Journal of …, 2011 - journals.lww.com
Objectives Many angiotensin receptor blocker (ARB) monotherapy patients need at least two
agents to control blood pressure (BP). We investigated whether initiating intensive treatment …

Effectiveness and safety of valsartan in children aged 6 to 16 years with hypertension

T Wells, J Blumer, KEC Meyers… - The Journal of …, 2011 - Wiley Online Library
The effectiveness and safety of valsartan have not been assessed in hypertensive children.
Therefore, hypertensive patients aged 6 to 16 years (n= 261) were randomized to receive …

The efficacy and safety of valsartan and combination of valsartan and hydrochlorothiazide in the treatment of patients with mild to moderate arterial hypertension—the …

IY Chazova, Y Sirenko, J Vincelj… - Polish Heart …, 2017 - journals.viamedica.pl
Background and aim: The aim of the trial was to establish the efficacy and safety of
Valsacor®(valsartan) and Valsacombi®(combination of valsartan and hydrochlorothiazide) …

Antihypertensive effects of valsartan/hydrochlorothiazide combination in essential hypertension

A Schmidt, SA Adam, R Kolloch, G Weidinger… - Blood …, 2001 - Taylor & Francis
Fixed-dose combination therapy has received increased interest since publication of JNC-VI
report and WHO/ISH guidelines 1999. We compared in a randomized, double-blind study …

Antihypertensive efficacy and safety of olmesartan and ramipril in elderly patients with mild to moderate systolic and diastolic essential hypertension

JM Mallion, S Omboni, J Barton, W Van Mieghem… - Blood …, 2011 - Taylor & Francis
Objective. To compare the efficacy and safety of olmesartan medoxomil (O) and ramipril (R)
in elderly patients with essential arterial hypertension. Methods. After a 2-week placebo …

Valsartan/hydrochlorothiazide: pharmacology and clinical efficacy

R Kondrack, S Mohiuddin - Expert opinion on drug metabolism & …, 2009 - Taylor & Francis
Background: Valsartan/hydrochlorothiazide is a combination of an angiotensin II receptor
antagonist and diuretic indicated for hypertensive patients as initial therapy and those not …

Efficacy and safety of valsartan compared with enalapril at different altitudes

R Botero, H Matiz, E Marıa, H Orejarena… - International journal of …, 2000 - Elsevier
Objective: To compare the safety, tolerability, and antihypertensive efficacy of valsartan with
enalapril at different altitudes. Method: A total of 142 adult Colombian outpatients with mild …

Effects of valsartan/hydrochlorothiazide and amlodipine on ambulatory blood pressure and plasma norepinephrine levels in high-risk hypertensive patients

E Malacco, S Piazza, L Scandiani, A Zoppi - Advances in therapy, 2004 - Springer
The efficacy and tolerability of the combination of valsartan and hydrochlorothi-azide (HCTZ)
were compared with that of amlodipine in reducing ambulatory blood pressure and plasma …

Impact of angiotensin receptor blockade in combination with hydrochlorothiazide 25 mg in 2121 patients with stage 1–2 hypertension

WB White, G Davidai, H Schumacher - Journal of human hypertension, 2009 - nature.com
The antihypertensive effects of telmisartan 80 mg versus valsartan 160 mg, both combined
with hydrochlorothiazide (HCTZ) 25 mg, were assessed in a pooled analysis from two large …