Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …

An individual's brainAGE is the difference between chronological age and age predicted
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …

The cosmetic and behavioural aspects of ageing become increasingly apparent with the
passing years. The individual variability in physical ageing can be immediately observed in …

The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …

Brain imaging can be used to study how individuals' brains are aging, compared against
population norms. This can inform on aspects of brain health; for example, smoking and …

It is of increasing interest to study “brain age”-the apparent age of a subject, as inferred from
brain imaging data. The difference between brain age and actual age (the “delta”) is typically …

Brain age is a metric that quantifies the degree of aging of a brain based on whole-brain
anatomical characteristics. While associations between individual human brain regions and …

Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …

Early-life development is characterized by dramatic changes, impacting lifespan function
more than changes in any other period. Developmental origins of neurocognitive late-life …