Pharmacodynamics of piperacillin alone and in combination with tazobactam against piperacillin-resistant and-susceptible organisms in an in vitro model of infection
AH Strayer, DH Gilbert, P Pivarnik… - Antimicrobial agents …, 1994 - Am Soc Microbiol
The pharmacodynamics of dosage regimens of piperacillin alone or in combination with
tazobactam against piperacillin-resistant or-susceptible bacteria were studied in an in vitro …
tazobactam against piperacillin-resistant or-susceptible bacteria were studied in an in vitro …
Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid
P Van Der Auwera, V Duchateau… - Antimicrobial agents …, 1993 - Am Soc Microbiol
Ten volunteers received piperacillin (4 g), piperacillin (4 g) plus tazobactam (0.5 g)(Tazocin),
and ticarcillin (3 g) plus clavulanic acid (0.2 g)(Timentin) intravenously over 30 min in a …
and ticarcillin (3 g) plus clavulanic acid (0.2 g)(Timentin) intravenously over 30 min in a …
Pharmacokinetics and pharmacodynamics of two multiple-dose piperacillin-tazobactam regimens
DJ Occhipinti, SL Pendland… - Antimicrobial agents …, 1997 - Am Soc Microbiol
The pharmacokinetics and pharmacodynamics of two multiple-dose regimens of piperacillin-
tazobactam (3.375 g every 6 h and 4.5 g every 8 h) were evaluated at steady state for 12 …
tazobactam (3.375 g every 6 h and 4.5 g every 8 h) were evaluated at steady state for 12 …
Pharmacokinetics of piperacillin–tazobactam: intermittent dosing versus continuous infusion
C Buck, N Bertram, T Ackermann, T Sauerbruch… - International journal of …, 2005 - Elsevier
In the present study 24 hospitalized patients requiring empirical antibiotic treatment were
randomly assigned to receive the β-lactam antibiotic/β-lactamase inhibitor combination …
randomly assigned to receive the β-lactam antibiotic/β-lactamase inhibitor combination …
Pharmacokinetic characteristics of piperacillin/tazobactam
F Sörgel, M Kinzig - Intensive care medicine, 1994 - Springer
Piperacillin/tazobactam is a new combination of a broad-spectrum penicillin and a beta-
lactamase inhibitor. In studies in healthy volunteers, the pharmacokinetics of piperacillin …
lactamase inhibitor. In studies in healthy volunteers, the pharmacokinetics of piperacillin …
Pharmacokinetic and pharmacodynamic evaluation of two dosing regimens for piperacillin‐tazobactam
MK Kim, B Capitano, HM Mattoes… - … : The Journal of …, 2002 - Wiley Online Library
Study Objective. To compare the pharmacokinetic and pharmacodynamic profiles of two
dosing regimens for piperacillin‐tazobactam against commonly encountered pathogens …
dosing regimens for piperacillin‐tazobactam against commonly encountered pathogens …
Pharmacokinetic-pharmacodynamic modelling of the in vitro antiinfective effect of piperacillin-tazobactam combinations.
T Dalla Costa, A Nolting, K Rand… - International journal of …, 1997 - europepmc.org
Purpose The aim of the study was to investigate the in vitro antiinfective effect of piperacillin-
tazobactam (PIP-TZB) combinations on Escherichia coli in simulations of free concentration …
tazobactam (PIP-TZB) combinations on Escherichia coli in simulations of free concentration …
Steady-state pharmacokinetics and pharmacodynamics of piperacillin/tazobactam administered by prolonged infusion in hospitalised patients
KM Shea, SC Cheatham, MF Wack, DW Smith… - International journal of …, 2009 - Elsevier
The objective of this study was to evaluate the steady-state pharmacokinetics and
pharmacodynamics of piperacillin/tazobactam, administered by prolonged infusion, in …
pharmacodynamics of piperacillin/tazobactam, administered by prolonged infusion, in …
In vitro pharmacodynamics of piperacillin, piperacillin-tazobactam, and ciprofloxacin alone and in combination against Staphylococcus aureus, Klebsiella pneumoniae …
JM Hyatt, DE Nix, CW Stratton… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The time-kill curve methodology was used to determine the pharmacodynamics of
piperacillin, ciprofloxacin, piperacillin-tazobactam and the combinations piperacillin …
piperacillin, ciprofloxacin, piperacillin-tazobactam and the combinations piperacillin …
Comparative in vitro activities of piperacillin-tazobactam and ticarcillin-clavulanate
RJ Fass, RB Prior - Antimicrobial agents and chemotherapy, 1989 - Am Soc Microbiol
The in vitro activities of ticarcillin, piperacillin, clavulanic acid, tazobactam, ticarcillin-
clavulanate, and piperacillin-tazobactam against 819 bacterial isolates were compared. The …
clavulanate, and piperacillin-tazobactam against 819 bacterial isolates were compared. The …