Barriers and facilitators to enrollment in cancer clinical trials: qualitative study of the perspectives of clinical research associates

E Grunfeld, L Zitzelsberger, M Coristine, F Aspelund - Cancer, 2002 - Wiley Online Library
BACKGROUND The literature continues to report low rates of accrual to cancer clinical trials.
Previous studies have examined principally physician‐related or patient‐related barriers …

Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment

PN Lara Jr, R Higdon, N Lim, K Kwan… - Journal of clinical …, 2001 - ascopubs.org
PURPOSE: Well-conducted cancer clinical trials are essential for improving patient
outcomes. Unfortunately, only 3% of new cancer patients participate in clinical trials. Barriers …

Obstacles to the accrual of patients to clinical trials in the community setting.

RJ Winn - Seminars in Oncology, 1994 - europepmc.org
Data indicate that substantial pool of candidates exists, especially in the community setting,
for enrollment in clinical oncologic trials. However, only a small proportion of cancer patients …

[HTML][HTML] Barriers to participation in clinical trials: a physician survey

A Mahmud, O Zalay, A Springer, K Arts… - Current …, 2018 - pmc.ncbi.nlm.nih.gov
Background Clinical trials are vital for evidence-based cancer care. Oncologist engagement
in clinical trials has an effect on patient recruitment, which in turn can affect trial success …

Effect of medical oncologists' attitudes on accrual to clinical trials in a community setting

CP Somkin, L Ackerson, G Husson, V Gomez… - Journal of oncology …, 2013 - ascopubs.org
Purpose: Oncology clinical trials (OCTs) are crucial in evaluating new cancer treatments, but
only 2% to 3% of US adult patients with cancer enter OCTs. This study assessed barriers to …

[HTML][HTML] Barriers for cancer clinical trial enrollment: a qualitative study of the perspectives of healthcare providers

G Kumar, P Chaudhary, A Quinn, D Su - Contemporary Clinical Trials …, 2022 - Elsevier
Background Barriers to clinical trial enrollment have been the subject of extensive research;
however, the rate of clinical trial participation has not improved significantly over time …

Improving accrual into cancer clinical trials

JF Foley, CG Moertel - Journal of Cancer Education, 1991 - Taylor & Francis
It is thought by some that there are inadequate patient entries on high priority national
cancer treatment protocols, resulting in intolerable delays in addressing crucial research …

Clinical trial awareness, attitudes, and participation among patients with cancer and oncologists

L Fenton, M Rigney, RS Herbst - Community Oncology, 2009 - infona.pl
Low accrual rates may affect the completion of clinical trials essential to the development of
new cancer therapies. Patient and physician attitudes and awareness of clinical trials …

Barriers to recruitment of rural patients in cancer clinical trials

S Virani, L Burke, SC Remick… - Journal of oncology …, 2011 - ascopubs.org
Purpose: The National Cancer Institute estimates that less than 5% of adult patients with
cancer participate in clinical trials. This statistic has to improve in order for clinical trials to be …

An evaluation of barriers to accrual in the era of legislation requiring insurance coverage of cancer clinical trial costs in California

CL Mattel, Y Li, L Beckett, H Chew… - The Cancer …, 2004 - journals.lww.com
PURPOSE Clinical trials are essential to improve cancer therapy, but only 3% of newly
diagnosed adult cancer patients enroll annually. We previously conducted a prospective …