Abstract Serotonin (5‐HT) exerts excitatory effects in many brainstem regions involved in
autonomic, somatic, motor, and sensory functions, and in control of vigilance. To determine …

Summary The effects of 5-hydroxytryptamine (5-HT), noradrenaline (NA) and stimulation of
the inferior central nucleus of the raphe (RN) were examined on nociceptive and non …

There is a general agreement concerning the key role of the baroreceptor reflex in blood
pressure homeostasis. It is also well accepted that baroreceptor afferent messages are first …

The serotonin-containing raphe-spinal pathway has been implicated as playing an important
role in analgesia. Several studies, however, have reported the inefficacy of traditional …

Serotonin (5-HT) plays a major yet complex role in modulating spinal nociceptive
transmission as a consequence of the number of 5-HT receptor subtypes. These include the …

Serotonin 5-HT 3 receptors are abundant in the superficial dorsal horn and are likely to have
an involvement in processing of nociceptive information. It has been shown previously that 5 …

The lateral reticular nucleus (LRN) in the caudal ventrolateral medulia has been implicated
in descending monoaminergic modulation of spinal nociceptive transmission. Experiments …

The organization in the brainstem of descending pathways of spinal inhibition was
examined in the lightly pentobarbital-anesthetized rat. Thresholds for focal electrical …

The modulatory effect of spinal serotonin (5-HT) 1 receptors on nociception was studied in
mice. 8-Hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) and buspirone, putative 5-HT1A …

Employing the Nystatin-perforated whole-cell patch-clamp recording technique, the
modulatory effects of serotonin (5-HT) on γ-aminobutyric acid (GABA)-activated whole-cell …