Mitochondria play a vital role in embryo development. They are the principal site of energy
production and have various other critical cellular functions. Despite the importance of this …

STUDY QUESTION Can quantification of mitochondrial DNA (mtDNA) in trophectoderm (TE)
biopsy samples provide information concerning the viability of a blastocyst, potentially …

Purpose The aim was to study the association between embryonal mitochondrial DNA
(mtDNA) content and embryo quality and implantation outcomes. Methods A retrospective …

STUDY QUESTION Does the amount of mitochondrial DNA (mtDNA) in blastocyst biopsy
specimens have the potential to serve as a biomarker of euploid embryo implantation ability …

STUDY QUESTION What is the predictive value of trophectoderm mitochondrial DNA
(mtDNA) quantity for blastocyst reproductive potential? SUMMARY ANSWER This study …

Objective To investigate the clinical relevance of mitochondrial DNA (mtDNA) content as a
viability score in human euploid embryos. Design Retrospective analysis of mtDNA content …

There is increasing evidence in humans that abnormal mitochondrial DNA (mtDNA) is
associated with common degenerative disorders of the twenty-first century. MtDNA is …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

Objective To accurately determine mitochondrial DNA (mtDNA) levels in human blastocysts.
Design Retrospective analysis. Setting IVF clinic. Patient (s) A total of 1,396 embryos derived …

Recent reports of strong selection of mitochondrial DNA (mtDNA) during transmission in
animal models of mtDNA disease, and of nuclear transfer in both animal models and …