SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes

I Fernández-Ruiz - Nature Reviews Cardiology, 2024 - nature.com
Treatment with the glucagon-like peptide 1 receptor agonist semaglutide, administered
subcutaneously at a dose of 2.4 mg once per week, reduces the risk of major cardiovascular …

[HTML][HTML] Semaglutide and cardiovascular outcomes in obesity without diabetes

AM Lincoff, K Brown-Frandsen… - … England Journal of …, 2023 - Mass Medical Soc
Background Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to
reduce the risk of adverse cardiovascular events in patients with diabetes. Whether …

[HTML][HTML] SELECT: Glucagon-like peptide-1 receptor agonist in obese patients with cardiovascular disease in the absence of diabetes

S Kotit, M Sous - Global Cardiology Science & Practice, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: Obesity is a global epidemic affecting 2.5 billion people and is recognized as
the fourth leading cause of global mortality. Obesity is characterized by excessive …

Semaglutide and cardiovascular outcomes in obesity without diabetes

D Yavuz - 2023 - openaccess.marmara.edu.tr
Background: Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to
reduce the risk of adverse cardiovascular events in patients with diabetes. Whether …

SELECT semaglutide to improve outcomes in patients with obesity and cardiovascular disease, also without diabetes

G Gajos - Cardiology Journal, 2024 - journals.viamedica.pl
More than half the world population is expected to be overweight or obese by the year 2035
[1]. Obesity and atherosclerotic cardiovascular disease have always been a fatal …

The SELECT trial of semaglutide in patients with overweight or obesity without diabetes: establishing a new pathway to secondary prevention of cardiovascular …

AM Lincoff, DH Ryan - 2024 - academic.oup.com
Overweight or obesity has been independently associated with increased cardiovascular
risk, yet interventional trials of lifestyle or pharmacologic management strategies for …

[引用][C] Beneficial cardio‐metabolic effects of semaglutide in individuals living with overweight/obesity without type 2 diabetes. Additional analysis of the SELECT trial

I Idris - 2024 - Wiley Online Library
Previous studies have shown benefits of the Glucagon-like peptide (GLP-1) receptor agonist
Semaglutide (Wegovy, Ozempic) to reduce cardiovascular events in overweight/obese …

Reducing cardiovascular outcomes with semaglutide: a metabolic route for a SELECT few

G Liuzzo, C Patrono - 2024 - academic.oup.com
• In the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or
Obesity trial, the SELECT Investigators tested the hypothesis that the addition of …

[引用][C] High dose semaglutide 2.4 mg (once weekly) shown to reduce the risks of cardiovascular events in people without diabetes

I Idris - 2023 - Wiley Online Library
Conclusive evidence have shown the cardiovascular benefits of semaglutide (1 mg weekly)
in people with type 2 diabetes. 1 Recent data have also confirmed the efficacy of high dose …

Comment on: Semaglutide and cardiovascular outcomes in obesity without diabetes

A Basolo, P Fierabracci, G Salvetti, F Santini - Journal of Endocrinological …, 2024 - Springer
The independent association between overweight, obesity, and an increased risk of
cardiovascular events emphasizes the urgent need for effective interventions to mitigate this …